Polygenic risk score across distinct colorectal cancer screening outcomes: from premalignant polyps to colorectal cancer

Polygenic risk score across distinct colorectal cancer screening outcomes: from premalignant polyps to colorectal cancer

Abstract Background Different risk-based colorectal cancer (CRC) screening strategies, such as the use of polygenic risk scores (PRS), have been evaluated to improve effectiveness of these programs. However, few studies have previously assessed its usefulness in a fecal immunochemical test (FIT)-bas...

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Autores principales: Mireia Obón-Santacana, Anna Díez-Villanueva, Maria Henar Alonso, Gemma Ibáñez-Sanz, Elisabet Guinó, Ana López, Lorena Rodríguez-Alonso, Alfredo Mata, Ana García-Rodríguez, Andrés García Palomo, Antonio J. Molina, Montse Garcia, Gemma Binefa, Vicente Martín, Victor Moreno
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
Polygenic risk score
Colorectal cancer
Screening
Positive fecal immunochemical test
Positive predictive value
Negative predictive value
Medicine
R
Acceso en línea:https://doaj.org/article/733185c3c65f446a9006a4acf155d6ce
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https://doaj.org/article/733185c3c65f446a9006a4acf155d6ce

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