Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S

Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S

Endoglycosidase S only recognizes one particular type of glycan within IgG antibodies but the molecular basis for this high specificity is not fully understood. Here, the authors present the crystal structure of product-bound Endoglycosidase S, revealing the determinants for its glycan specificity.

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Autores principales: Beatriz Trastoy, Erik Klontz, Jared Orwenyo, Alberto Marina, Lai-Xi Wang, Eric J. Sundberg, Marcelo E. Guerin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
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Acceso en línea:https://doaj.org/article/733a7aaf8d0e4ff182ca5cc6f40ca189
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