Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation

HIV particles contain a relatively low amount of viral envelope (Env), but underlying packaging mechanisms are poorly understood. Here, the authors use superresolution microscopy and show that Env distribution is biased toward the necks of cell-associated particles during assembly.

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Autores principales:	Carmen A. Buttler, Nairi Pezeshkian, Melissa V. Fernandez, Jesse Aaron, Sofya Norman, Eric O. Freed, Schuyler B. van Engelenburg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/734cdebcccc14d6ca52e73e1f0d3d8d8
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spelling	oai:doaj.org-article:734cdebcccc14d6ca52e73e1f0d3d8d82021-12-02T15:33:58ZSingle molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation10.1038/s41467-018-04220-w2041-1723https://doaj.org/article/734cdebcccc14d6ca52e73e1f0d3d8d82018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04220-whttps://doaj.org/toc/2041-1723HIV particles contain a relatively low amount of viral envelope (Env), but underlying packaging mechanisms are poorly understood. Here, the authors use superresolution microscopy and show that Env distribution is biased toward the necks of cell-associated particles during assembly.Carmen A. ButtlerNairi PezeshkianMelissa V. FernandezJesse AaronSofya NormanEric O. FreedSchuyler B. van EngelenburgNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Carmen A. Buttler Nairi Pezeshkian Melissa V. Fernandez Jesse Aaron Sofya Norman Eric O. Freed Schuyler B. van Engelenburg Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation
description	HIV particles contain a relatively low amount of viral envelope (Env), but underlying packaging mechanisms are poorly understood. Here, the authors use superresolution microscopy and show that Env distribution is biased toward the necks of cell-associated particles during assembly.
format	article
author	Carmen A. Buttler Nairi Pezeshkian Melissa V. Fernandez Jesse Aaron Sofya Norman Eric O. Freed Schuyler B. van Engelenburg
author_facet	Carmen A. Buttler Nairi Pezeshkian Melissa V. Fernandez Jesse Aaron Sofya Norman Eric O. Freed Schuyler B. van Engelenburg
author_sort	Carmen A. Buttler
title	Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation
title_short	Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation
title_full	Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation
title_fullStr	Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation
title_full_unstemmed	Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation
title_sort	single molecule fate of hiv-1 envelope reveals late-stage viral lattice incorporation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/734cdebcccc14d6ca52e73e1f0d3d8d8
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Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation

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