Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation

HIV particles contain a relatively low amount of viral envelope (Env), but underlying packaging mechanisms are poorly understood. Here, the authors use superresolution microscopy and show that Env distribution is biased toward the necks of cell-associated particles during assembly.

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Bibliographic Details
Main Authors: Carmen A. Buttler, Nairi Pezeshkian, Melissa V. Fernandez, Jesse Aaron, Sofya Norman, Eric O. Freed, Schuyler B. van Engelenburg
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/734cdebcccc14d6ca52e73e1f0d3d8d8
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