Neuroimaging Features of Optic Nerve Hemangioblastoma Identified by Conventional and Advanced Magnetic Resonance Techniques: A Case Report and Literature Review

Optic nerve hemangioblastoma is a very rare benign tumor with only 39 reported cases by now. It appears to be hyperintense on T2-weighted images with a significant enhancement on contrast scans, which are similar to glioma and meningioma. Due to the lack of specificity in MRI manifestations, optic n...

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Autores principales:	Meihan Duan, Lie Yang, Jun Kang, Renzhi Wang, Hui You, Ming Feng
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	neuroimaging magnetic resonance imaging (MRI) optic nerve hemangioblastoma diffusion-weighted imaging (DWI) apparent diffusion coefficient (ADC) angiography Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/7367c204085c44cda548bdddc43db77d
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spelling	oai:doaj.org-article:7367c204085c44cda548bdddc43db77d2021-11-12T04:27:20ZNeuroimaging Features of Optic Nerve Hemangioblastoma Identified by Conventional and Advanced Magnetic Resonance Techniques: A Case Report and Literature Review2234-943X10.3389/fonc.2021.763696https://doaj.org/article/7367c204085c44cda548bdddc43db77d2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.763696/fullhttps://doaj.org/toc/2234-943XOptic nerve hemangioblastoma is a very rare benign tumor with only 39 reported cases by now. It appears to be hyperintense on T2-weighted images with a significant enhancement on contrast scans, which are similar to glioma and meningioma. Due to the lack of specificity in MRI manifestations, optic nerve hemangioblastoma is often misdiagnosed. To provide new insights into differential diagnosis of optic nerve hemangioblastoma, we report for the first time an optic nerve hemangioblastoma case employing advanced magnetic resonance techniques including diffusion-weighted imaging (DWI), apparent diffusion coefficient (ADC) maps, and magnetic resonance angiography (MRA). In addition, we have collected all reported optic nerve hemangioblastoma cases and reviewed their neuroimaging findings by MRI and angiography. Our results show that solid-type tumor is the dominant form of optic nerve hemangioblastoma and extensive edema is widely observed. These findings are surprisingly contrary to manifestations of cerebellar hemangioblastoma. Besides the structural features, quantitative indexes including ADC and relative cerebral blood volume (rCBV) ratio, which are significantly elevated in cerebellar hemangioblastoma, may also shed a light on the preoperative diagnosis of hemangioblastoma of optic nerve. Finally, we discuss the critical neuroimaging features in the differential diagnosis between optic nerve hemangioblastoma from optic pathway glioma and optic nerve sheath meningioma.Meihan DuanLie YangJun KangRenzhi WangHui YouMing FengFrontiers Media S.A.articleneuroimagingmagnetic resonance imaging (MRI)optic nerve hemangioblastomadiffusion-weighted imaging (DWI)apparent diffusion coefficient (ADC)angiographyNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	neuroimaging magnetic resonance imaging (MRI) optic nerve hemangioblastoma diffusion-weighted imaging (DWI) apparent diffusion coefficient (ADC) angiography Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	neuroimaging magnetic resonance imaging (MRI) optic nerve hemangioblastoma diffusion-weighted imaging (DWI) apparent diffusion coefficient (ADC) angiography Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Meihan Duan Lie Yang Jun Kang Renzhi Wang Hui You Ming Feng Neuroimaging Features of Optic Nerve Hemangioblastoma Identified by Conventional and Advanced Magnetic Resonance Techniques: A Case Report and Literature Review
description	Optic nerve hemangioblastoma is a very rare benign tumor with only 39 reported cases by now. It appears to be hyperintense on T2-weighted images with a significant enhancement on contrast scans, which are similar to glioma and meningioma. Due to the lack of specificity in MRI manifestations, optic nerve hemangioblastoma is often misdiagnosed. To provide new insights into differential diagnosis of optic nerve hemangioblastoma, we report for the first time an optic nerve hemangioblastoma case employing advanced magnetic resonance techniques including diffusion-weighted imaging (DWI), apparent diffusion coefficient (ADC) maps, and magnetic resonance angiography (MRA). In addition, we have collected all reported optic nerve hemangioblastoma cases and reviewed their neuroimaging findings by MRI and angiography. Our results show that solid-type tumor is the dominant form of optic nerve hemangioblastoma and extensive edema is widely observed. These findings are surprisingly contrary to manifestations of cerebellar hemangioblastoma. Besides the structural features, quantitative indexes including ADC and relative cerebral blood volume (rCBV) ratio, which are significantly elevated in cerebellar hemangioblastoma, may also shed a light on the preoperative diagnosis of hemangioblastoma of optic nerve. Finally, we discuss the critical neuroimaging features in the differential diagnosis between optic nerve hemangioblastoma from optic pathway glioma and optic nerve sheath meningioma.
format	article
author	Meihan Duan Lie Yang Jun Kang Renzhi Wang Hui You Ming Feng
author_facet	Meihan Duan Lie Yang Jun Kang Renzhi Wang Hui You Ming Feng
author_sort	Meihan Duan
title	Neuroimaging Features of Optic Nerve Hemangioblastoma Identified by Conventional and Advanced Magnetic Resonance Techniques: A Case Report and Literature Review
title_short	Neuroimaging Features of Optic Nerve Hemangioblastoma Identified by Conventional and Advanced Magnetic Resonance Techniques: A Case Report and Literature Review
title_full	Neuroimaging Features of Optic Nerve Hemangioblastoma Identified by Conventional and Advanced Magnetic Resonance Techniques: A Case Report and Literature Review
title_fullStr	Neuroimaging Features of Optic Nerve Hemangioblastoma Identified by Conventional and Advanced Magnetic Resonance Techniques: A Case Report and Literature Review
title_full_unstemmed	Neuroimaging Features of Optic Nerve Hemangioblastoma Identified by Conventional and Advanced Magnetic Resonance Techniques: A Case Report and Literature Review
title_sort	neuroimaging features of optic nerve hemangioblastoma identified by conventional and advanced magnetic resonance techniques: a case report and literature review
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/7367c204085c44cda548bdddc43db77d
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_version_	1718431296825327616

Neuroimaging Features of Optic Nerve Hemangioblastoma Identified by Conventional and Advanced Magnetic Resonance Techniques: A Case Report and Literature Review

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