Paraneoplastic myopathy in pancreatic cancer: a case report and literature review

Dermatomyositis (DM) and polymyositis (PM) are both immune-mediated inflammatory myopathies known to occur in paraneoplastic syndromes associated with a new diagnosis of malignancy, most commonly breast, ovarian, lung, pancreatic, stomach, colorectal, and Non-Hodgkin’s lymphoma1 in DM and breast, lu...

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Autores principales:	Jessica Joanne Padniewski, Elizabeth Nelson, Istiaq Mian, Andrew Laczniak, Samuel Ives, Rawad Nasr
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2021
Materias:	paraneoplastic myopathy paraneoplastic myositis paraneoplastic syndrome pancreatic cancer myopathy Internal medicine RC31-1245
Acceso en línea:	https://doaj.org/article/737608112a204efd80d97bafb1469958
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spelling	oai:doaj.org-article:737608112a204efd80d97bafb14699582021-11-17T14:21:57ZParaneoplastic myopathy in pancreatic cancer: a case report and literature review2000-966610.1080/20009666.2021.1982487https://doaj.org/article/737608112a204efd80d97bafb14699582021-11-01T00:00:00Zhttp://dx.doi.org/10.1080/20009666.2021.1982487https://doaj.org/toc/2000-9666Dermatomyositis (DM) and polymyositis (PM) are both immune-mediated inflammatory myopathies known to occur in paraneoplastic syndromes associated with a new diagnosis of malignancy, most commonly breast, ovarian, lung, pancreatic, stomach, colorectal, and Non-Hodgkin’s lymphoma1 in DM and breast, lung, bladder cancer, and Non-Hodgkin’s lymphoma in PM. 2,3,4 While inflammatory markers such as creatine kinase (CK) may be elevated with either DM or PM, marked elevation is rare. Herein, we report a case of newly diagnosed pancreatic cancer presenting with inflammatory myopathy and marked CK elevation. We review the frequency of PM as a paraneoplastic syndrome, the association with marked CK elevation, and the association with pancreatic cancer.Jessica Joanne PadniewskiElizabeth NelsonIstiaq MianAndrew LaczniakSamuel IvesRawad NasrTaylor & Francis Grouparticleparaneoplastic myopathyparaneoplastic myositisparaneoplastic syndromepancreatic cancermyopathyInternal medicineRC31-1245ENJournal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 6, Pp 847-851 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	paraneoplastic myopathy paraneoplastic myositis paraneoplastic syndrome pancreatic cancer myopathy Internal medicine RC31-1245
spellingShingle	paraneoplastic myopathy paraneoplastic myositis paraneoplastic syndrome pancreatic cancer myopathy Internal medicine RC31-1245 Jessica Joanne Padniewski Elizabeth Nelson Istiaq Mian Andrew Laczniak Samuel Ives Rawad Nasr Paraneoplastic myopathy in pancreatic cancer: a case report and literature review
description	Dermatomyositis (DM) and polymyositis (PM) are both immune-mediated inflammatory myopathies known to occur in paraneoplastic syndromes associated with a new diagnosis of malignancy, most commonly breast, ovarian, lung, pancreatic, stomach, colorectal, and Non-Hodgkin’s lymphoma1 in DM and breast, lung, bladder cancer, and Non-Hodgkin’s lymphoma in PM. 2,3,4 While inflammatory markers such as creatine kinase (CK) may be elevated with either DM or PM, marked elevation is rare. Herein, we report a case of newly diagnosed pancreatic cancer presenting with inflammatory myopathy and marked CK elevation. We review the frequency of PM as a paraneoplastic syndrome, the association with marked CK elevation, and the association with pancreatic cancer.
format	article
author	Jessica Joanne Padniewski Elizabeth Nelson Istiaq Mian Andrew Laczniak Samuel Ives Rawad Nasr
author_facet	Jessica Joanne Padniewski Elizabeth Nelson Istiaq Mian Andrew Laczniak Samuel Ives Rawad Nasr
author_sort	Jessica Joanne Padniewski
title	Paraneoplastic myopathy in pancreatic cancer: a case report and literature review
title_short	Paraneoplastic myopathy in pancreatic cancer: a case report and literature review
title_full	Paraneoplastic myopathy in pancreatic cancer: a case report and literature review
title_fullStr	Paraneoplastic myopathy in pancreatic cancer: a case report and literature review
title_full_unstemmed	Paraneoplastic myopathy in pancreatic cancer: a case report and literature review
title_sort	paraneoplastic myopathy in pancreatic cancer: a case report and literature review
publisher	Taylor & Francis Group
publishDate	2021
url	https://doaj.org/article/737608112a204efd80d97bafb1469958
work_keys_str_mv	AT jessicajoannepadniewski paraneoplasticmyopathyinpancreaticcanceracasereportandliteraturereview AT elizabethnelson paraneoplasticmyopathyinpancreaticcanceracasereportandliteraturereview AT istiaqmian paraneoplasticmyopathyinpancreaticcanceracasereportandliteraturereview AT andrewlaczniak paraneoplasticmyopathyinpancreaticcanceracasereportandliteraturereview AT samuelives paraneoplasticmyopathyinpancreaticcanceracasereportandliteraturereview AT rawadnasr paraneoplasticmyopathyinpancreaticcanceracasereportandliteraturereview
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Paraneoplastic myopathy in pancreatic cancer: a case report and literature review

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