Targeting of PBP1 by β-lactams determines recA/SOS response activation in heterogeneous MRSA clinical strains.
The SOS response, a conserved regulatory network in bacteria that is induced in response to DNA damage, has been shown to be associated with the emergence of resistance to antibiotics. Previously, we demonstrated that heterogeneous (HeR) MRSA strains, when exposed to sub-inhibitory concentrations of...
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Autores principales: | Konrad B Plata, Sarah Riosa, Christopher R Singh, Roberto R Rosato, Adriana E Rosato |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/737694b2f97549d9849a6d8c280f0948 |
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