Targeting of PBP1 by β-lactams determines recA/SOS response activation in heterogeneous MRSA clinical strains.

The SOS response, a conserved regulatory network in bacteria that is induced in response to DNA damage, has been shown to be associated with the emergence of resistance to antibiotics. Previously, we demonstrated that heterogeneous (HeR) MRSA strains, when exposed to sub-inhibitory concentrations of...

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Auteurs principaux: Konrad B Plata, Sarah Riosa, Christopher R Singh, Roberto R Rosato, Adriana E Rosato
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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R
Q
Accès en ligne:https://doaj.org/article/737694b2f97549d9849a6d8c280f0948
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