Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus

The aim of the work was to evaluate the influence of the linimentfrom Pentaphylloides fruticosa L. on lipid peroxidation in rats with experimental diabetes mellitus accompanied by wound process. The liniment was developed with the use of NanoDeBee30 device. Experiments were carried out on white male...

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Autores principales: V. E. Khitrikheev, B. N. Garmaev, M. I. Balkhaev, I. G. Nikolaeva
Formato: article
Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2016
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Acceso en línea:https://doaj.org/article/7385a6a9db9244658f0b8b04b36f0b0b
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spelling oai:doaj.org-article:7385a6a9db9244658f0b8b04b36f0b0b2021-11-23T06:14:36ZInfluence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus2541-94202587-959610.12737/23407https://doaj.org/article/7385a6a9db9244658f0b8b04b36f0b0b2016-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/293https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The aim of the work was to evaluate the influence of the linimentfrom Pentaphylloides fruticosa L. on lipid peroxidation in rats with experimental diabetes mellitus accompanied by wound process. The liniment was developed with the use of NanoDeBee30 device. Experiments were carried out on white male Wistar rats. Experimental diabetes mellitus was simulated by a single intraperitoneal introduction of alloxan in a dose of 100 mg/kg. The skin injury was simulated by inflicting planar wounds 2.0 x 2.0 cm in size. 5 mg of the 5%-liniment from Pentaphylloides fruticosa was put on the wounds of the first experimental group once a day for 14 days. The second experimental group was treated by the preparation of comparison - balsamic liniment. The wounds of the control group were treated with glycerin-lanolin ointment. On the 7th, 14th and 21st day the concentration of TBA-active products in the blood serum was determined to estimate the intensity of lipid peroxidation processes; the contents of reduced glutathione and catalase activity were determined to evaluate the antioxidant status. The results of the experiments verify the marked curative effect of the linimentfrom Pentaphylloides fruticosa L. on the healing of the wounds on the background of experimental diabetes mellitus in ratsV. E. KhitrikheevB. N. GarmaevM. I. BalkhaevI. G. NikolaevaScientific Сentre for Family Health and Human Reproduction Problemsarticlepentaphylloides fruticosa l. linimentlipid peroxidationskin injurydiabetes mellitusScienceQRUActa Biomedica Scientifica, Vol 1, Iss 5, Pp 126-128 (2016)
institution DOAJ
collection DOAJ
language RU
topic pentaphylloides fruticosa l. liniment
lipid peroxidation
skin injury
diabetes mellitus
Science
Q
spellingShingle pentaphylloides fruticosa l. liniment
lipid peroxidation
skin injury
diabetes mellitus
Science
Q
V. E. Khitrikheev
B. N. Garmaev
M. I. Balkhaev
I. G. Nikolaeva
Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
description The aim of the work was to evaluate the influence of the linimentfrom Pentaphylloides fruticosa L. on lipid peroxidation in rats with experimental diabetes mellitus accompanied by wound process. The liniment was developed with the use of NanoDeBee30 device. Experiments were carried out on white male Wistar rats. Experimental diabetes mellitus was simulated by a single intraperitoneal introduction of alloxan in a dose of 100 mg/kg. The skin injury was simulated by inflicting planar wounds 2.0 x 2.0 cm in size. 5 mg of the 5%-liniment from Pentaphylloides fruticosa was put on the wounds of the first experimental group once a day for 14 days. The second experimental group was treated by the preparation of comparison - balsamic liniment. The wounds of the control group were treated with glycerin-lanolin ointment. On the 7th, 14th and 21st day the concentration of TBA-active products in the blood serum was determined to estimate the intensity of lipid peroxidation processes; the contents of reduced glutathione and catalase activity were determined to evaluate the antioxidant status. The results of the experiments verify the marked curative effect of the linimentfrom Pentaphylloides fruticosa L. on the healing of the wounds on the background of experimental diabetes mellitus in rats
format article
author V. E. Khitrikheev
B. N. Garmaev
M. I. Balkhaev
I. G. Nikolaeva
author_facet V. E. Khitrikheev
B. N. Garmaev
M. I. Balkhaev
I. G. Nikolaeva
author_sort V. E. Khitrikheev
title Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
title_short Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
title_full Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
title_fullStr Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
title_full_unstemmed Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
title_sort influence of the pentaphylloides fruticosa l. liniment on tba-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2016
url https://doaj.org/article/7385a6a9db9244658f0b8b04b36f0b0b
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AT bngarmaev influenceofthepentaphylloidesfruticosallinimentontbaactiveproductsandantioxidantstatusinwoundinjuriesassociatedwithexperimentaldiabetesmellitus
AT mibalkhaev influenceofthepentaphylloidesfruticosallinimentontbaactiveproductsandantioxidantstatusinwoundinjuriesassociatedwithexperimentaldiabetesmellitus
AT ignikolaeva influenceofthepentaphylloidesfruticosallinimentontbaactiveproductsandantioxidantstatusinwoundinjuriesassociatedwithexperimentaldiabetesmellitus
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