Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus

The aim of the work was to evaluate the influence of the linimentfrom Pentaphylloides fruticosa L. on lipid peroxidation in rats with experimental diabetes mellitus accompanied by wound process. The liniment was developed with the use of NanoDeBee30 device. Experiments were carried out on white male...

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Autores principales:	V. E. Khitrikheev, B. N. Garmaev, M. I. Balkhaev, I. G. Nikolaeva
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	pentaphylloides fruticosa l. liniment lipid peroxidation skin injury diabetes mellitus Science Q
Acceso en línea:	https://doaj.org/article/7385a6a9db9244658f0b8b04b36f0b0b
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spelling	oai:doaj.org-article:7385a6a9db9244658f0b8b04b36f0b0b2021-11-23T06:14:36ZInfluence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus2541-94202587-959610.12737/23407https://doaj.org/article/7385a6a9db9244658f0b8b04b36f0b0b2016-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/293https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The aim of the work was to evaluate the influence of the linimentfrom Pentaphylloides fruticosa L. on lipid peroxidation in rats with experimental diabetes mellitus accompanied by wound process. The liniment was developed with the use of NanoDeBee30 device. Experiments were carried out on white male Wistar rats. Experimental diabetes mellitus was simulated by a single intraperitoneal introduction of alloxan in a dose of 100 mg/kg. The skin injury was simulated by inflicting planar wounds 2.0 x 2.0 cm in size. 5 mg of the 5%-liniment from Pentaphylloides fruticosa was put on the wounds of the first experimental group once a day for 14 days. The second experimental group was treated by the preparation of comparison - balsamic liniment. The wounds of the control group were treated with glycerin-lanolin ointment. On the 7th, 14th and 21st day the concentration of TBA-active products in the blood serum was determined to estimate the intensity of lipid peroxidation processes; the contents of reduced glutathione and catalase activity were determined to evaluate the antioxidant status. The results of the experiments verify the marked curative effect of the linimentfrom Pentaphylloides fruticosa L. on the healing of the wounds on the background of experimental diabetes mellitus in ratsV. E. KhitrikheevB. N. GarmaevM. I. BalkhaevI. G. NikolaevaScientific Сentre for Family Health and Human Reproduction Problemsarticlepentaphylloides fruticosa l. linimentlipid peroxidationskin injurydiabetes mellitusScienceQRUActa Biomedica Scientifica, Vol 1, Iss 5, Pp 126-128 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	pentaphylloides fruticosa l. liniment lipid peroxidation skin injury diabetes mellitus Science Q
spellingShingle	pentaphylloides fruticosa l. liniment lipid peroxidation skin injury diabetes mellitus Science Q V. E. Khitrikheev B. N. Garmaev M. I. Balkhaev I. G. Nikolaeva Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
description	The aim of the work was to evaluate the influence of the linimentfrom Pentaphylloides fruticosa L. on lipid peroxidation in rats with experimental diabetes mellitus accompanied by wound process. The liniment was developed with the use of NanoDeBee30 device. Experiments were carried out on white male Wistar rats. Experimental diabetes mellitus was simulated by a single intraperitoneal introduction of alloxan in a dose of 100 mg/kg. The skin injury was simulated by inflicting planar wounds 2.0 x 2.0 cm in size. 5 mg of the 5%-liniment from Pentaphylloides fruticosa was put on the wounds of the first experimental group once a day for 14 days. The second experimental group was treated by the preparation of comparison - balsamic liniment. The wounds of the control group were treated with glycerin-lanolin ointment. On the 7th, 14th and 21st day the concentration of TBA-active products in the blood serum was determined to estimate the intensity of lipid peroxidation processes; the contents of reduced glutathione and catalase activity were determined to evaluate the antioxidant status. The results of the experiments verify the marked curative effect of the linimentfrom Pentaphylloides fruticosa L. on the healing of the wounds on the background of experimental diabetes mellitus in rats
format	article
author	V. E. Khitrikheev B. N. Garmaev M. I. Balkhaev I. G. Nikolaeva
author_facet	V. E. Khitrikheev B. N. Garmaev M. I. Balkhaev I. G. Nikolaeva
author_sort	V. E. Khitrikheev
title	Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
title_short	Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
title_full	Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
title_fullStr	Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
title_full_unstemmed	Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
title_sort	influence of the pentaphylloides fruticosa l. liniment on tba-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/7385a6a9db9244658f0b8b04b36f0b0b
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Influence of the Pentaphylloides fruticosa l. liniment on TBA-active products and antioxidant status in wound injuries associated with experimental diabetes mellitus

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