Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome

The Sc2.0 project has built the Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution (SCRaMbLE) system into their synthetic chromosomes. Here the authors use SCRaMbLE to rapidly develop, diversify and screen strains for diverse production and growth characteristics.

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Autores principales:	B. A. Blount, G-O. F. Gowers, J. C. H. Ho, R. Ledesma-Amaro, D. Jovicevic, R. M. McKiernan, Z. X. Xie, B. Z. Li, Y. J. Yuan, T. Ellis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/738aaf777cd743a989f5123aa889b4c7
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spelling	oai:doaj.org-article:738aaf777cd743a989f5123aa889b4c72021-12-02T16:56:53ZRapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome10.1038/s41467-018-03143-w2041-1723https://doaj.org/article/738aaf777cd743a989f5123aa889b4c72018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03143-whttps://doaj.org/toc/2041-1723The Sc2.0 project has built the Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution (SCRaMbLE) system into their synthetic chromosomes. Here the authors use SCRaMbLE to rapidly develop, diversify and screen strains for diverse production and growth characteristics.B. A. BlountG-O. F. GowersJ. C. H. HoR. Ledesma-AmaroD. JovicevicR. M. McKiernanZ. X. XieB. Z. LiY. J. YuanT. EllisNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q B. A. Blount G-O. F. Gowers J. C. H. Ho R. Ledesma-Amaro D. Jovicevic R. M. McKiernan Z. X. Xie B. Z. Li Y. J. Yuan T. Ellis Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome
description	The Sc2.0 project has built the Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution (SCRaMbLE) system into their synthetic chromosomes. Here the authors use SCRaMbLE to rapidly develop, diversify and screen strains for diverse production and growth characteristics.
format	article
author	B. A. Blount G-O. F. Gowers J. C. H. Ho R. Ledesma-Amaro D. Jovicevic R. M. McKiernan Z. X. Xie B. Z. Li Y. J. Yuan T. Ellis
author_facet	B. A. Blount G-O. F. Gowers J. C. H. Ho R. Ledesma-Amaro D. Jovicevic R. M. McKiernan Z. X. Xie B. Z. Li Y. J. Yuan T. Ellis
author_sort	B. A. Blount
title	Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome
title_short	Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome
title_full	Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome
title_fullStr	Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome
title_full_unstemmed	Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome
title_sort	rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/738aaf777cd743a989f5123aa889b4c7
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Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome

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