Enantiospecific electrochemical rearrangement for the synthesis of hindered triazolopyridinone derivatives

Chiral and hindered triazolopyridinone derivatives are an underexplored area of chemical space mainly due to their challenging synthesis via classical methods. Here, the authors report an electrochemical rearrangement for the synthesis of triazolopyridinones using diverse, available alkyl carboxylic...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zenghui Ye, Yanqi Wu, Na Chen, Hong Zhang, Kai Zhu, Mingruo Ding, Min Liu, Yong Li, Fengzhi Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/738cfb6b38a84e0f990f74d1bfe7f678
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:738cfb6b38a84e0f990f74d1bfe7f678
record_format dspace
spelling oai:doaj.org-article:738cfb6b38a84e0f990f74d1bfe7f6782021-12-02T16:26:25ZEnantiospecific electrochemical rearrangement for the synthesis of hindered triazolopyridinone derivatives10.1038/s41467-020-17389-w2041-1723https://doaj.org/article/738cfb6b38a84e0f990f74d1bfe7f6782020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17389-whttps://doaj.org/toc/2041-1723Chiral and hindered triazolopyridinone derivatives are an underexplored area of chemical space mainly due to their challenging synthesis via classical methods. Here, the authors report an electrochemical rearrangement for the synthesis of triazolopyridinones using diverse, available alkyl carboxylic acids as starting materials.Zenghui YeYanqi WuNa ChenHong ZhangKai ZhuMingruo DingMin LiuYong LiFengzhi ZhangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zenghui Ye
Yanqi Wu
Na Chen
Hong Zhang
Kai Zhu
Mingruo Ding
Min Liu
Yong Li
Fengzhi Zhang
Enantiospecific electrochemical rearrangement for the synthesis of hindered triazolopyridinone derivatives
description Chiral and hindered triazolopyridinone derivatives are an underexplored area of chemical space mainly due to their challenging synthesis via classical methods. Here, the authors report an electrochemical rearrangement for the synthesis of triazolopyridinones using diverse, available alkyl carboxylic acids as starting materials.
format article
author Zenghui Ye
Yanqi Wu
Na Chen
Hong Zhang
Kai Zhu
Mingruo Ding
Min Liu
Yong Li
Fengzhi Zhang
author_facet Zenghui Ye
Yanqi Wu
Na Chen
Hong Zhang
Kai Zhu
Mingruo Ding
Min Liu
Yong Li
Fengzhi Zhang
author_sort Zenghui Ye
title Enantiospecific electrochemical rearrangement for the synthesis of hindered triazolopyridinone derivatives
title_short Enantiospecific electrochemical rearrangement for the synthesis of hindered triazolopyridinone derivatives
title_full Enantiospecific electrochemical rearrangement for the synthesis of hindered triazolopyridinone derivatives
title_fullStr Enantiospecific electrochemical rearrangement for the synthesis of hindered triazolopyridinone derivatives
title_full_unstemmed Enantiospecific electrochemical rearrangement for the synthesis of hindered triazolopyridinone derivatives
title_sort enantiospecific electrochemical rearrangement for the synthesis of hindered triazolopyridinone derivatives
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/738cfb6b38a84e0f990f74d1bfe7f678
work_keys_str_mv AT zenghuiye enantiospecificelectrochemicalrearrangementforthesynthesisofhinderedtriazolopyridinonederivatives
AT yanqiwu enantiospecificelectrochemicalrearrangementforthesynthesisofhinderedtriazolopyridinonederivatives
AT nachen enantiospecificelectrochemicalrearrangementforthesynthesisofhinderedtriazolopyridinonederivatives
AT hongzhang enantiospecificelectrochemicalrearrangementforthesynthesisofhinderedtriazolopyridinonederivatives
AT kaizhu enantiospecificelectrochemicalrearrangementforthesynthesisofhinderedtriazolopyridinonederivatives
AT mingruoding enantiospecificelectrochemicalrearrangementforthesynthesisofhinderedtriazolopyridinonederivatives
AT minliu enantiospecificelectrochemicalrearrangementforthesynthesisofhinderedtriazolopyridinonederivatives
AT yongli enantiospecificelectrochemicalrearrangementforthesynthesisofhinderedtriazolopyridinonederivatives
AT fengzhizhang enantiospecificelectrochemicalrearrangementforthesynthesisofhinderedtriazolopyridinonederivatives
_version_ 1718384058032979968