Lymphoplasmacytic and eosinophilic enteritis with or without globule leukocyte hyperplasia in 4 goats

Abstract Four, mature, client‐owned goats were presented to referral hospitals for recurrent diarrhea despite treatment for intestinal parasitism. Common clinical findings included diarrhea, poor condition, neutrophilia, and hypoalbuminemia. Testing for common infectious causes of diarrhea in goats...

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Autores principales:	Mariya O. Pitel, Meera C. Heller, Jerry R. Roberson, Erica C. McKenzie, Devinn M. Sinnott, Verena K. Affolter
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	caprine hypoalbuminemia inflammatory bowel disease weight loss Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/739d91eeac164b6393958ee0e326a50d
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spelling	oai:doaj.org-article:739d91eeac164b6393958ee0e326a50d2021-11-30T17:01:05ZLymphoplasmacytic and eosinophilic enteritis with or without globule leukocyte hyperplasia in 4 goats1939-16760891-664010.1111/jvim.16110https://doaj.org/article/739d91eeac164b6393958ee0e326a50d2021-05-01T00:00:00Zhttps://doi.org/10.1111/jvim.16110https://doaj.org/toc/0891-6640https://doaj.org/toc/1939-1676Abstract Four, mature, client‐owned goats were presented to referral hospitals for recurrent diarrhea despite treatment for intestinal parasitism. Common clinical findings included diarrhea, poor condition, neutrophilia, and hypoalbuminemia. Testing for common infectious causes of diarrhea in goats was negative. Ultrasonography and computed tomography in 2 cases was suggestive of enteritis, including thickened intestinal walls and fluid filled, dilated small intestines, respectively. Lymphoplasmacytic and eosinophilic enteritis (LEE) was ultimately diagnosed on intestinal biopsy histopathology based on the presence of small intestinal villous blunting and increased numbers of lymphocytes and eosinophils predominantly within the lamina propria. Numerous globule leukocytes were also noted on histopathology in 3 cases. All goats responded favorably to corticosteroid treatment with weight gain and resolution of diarrhea and clinicopathologic abnormalities. Relapses occurred, and complete cure was difficult to achieve. Reported in other species, this series describes the clinical presentation, diagnosis, and treatment of LEE in adult goats.Mariya O. PitelMeera C. HellerJerry R. RobersonErica C. McKenzieDevinn M. SinnottVerena K. AffolterWileyarticlecaprinehypoalbuminemiainflammatory bowel diseaseweight lossVeterinary medicineSF600-1100ENJournal of Veterinary Internal Medicine, Vol 35, Iss 3, Pp 1620-1625 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	caprine hypoalbuminemia inflammatory bowel disease weight loss Veterinary medicine SF600-1100
spellingShingle	caprine hypoalbuminemia inflammatory bowel disease weight loss Veterinary medicine SF600-1100 Mariya O. Pitel Meera C. Heller Jerry R. Roberson Erica C. McKenzie Devinn M. Sinnott Verena K. Affolter Lymphoplasmacytic and eosinophilic enteritis with or without globule leukocyte hyperplasia in 4 goats
description	Abstract Four, mature, client‐owned goats were presented to referral hospitals for recurrent diarrhea despite treatment for intestinal parasitism. Common clinical findings included diarrhea, poor condition, neutrophilia, and hypoalbuminemia. Testing for common infectious causes of diarrhea in goats was negative. Ultrasonography and computed tomography in 2 cases was suggestive of enteritis, including thickened intestinal walls and fluid filled, dilated small intestines, respectively. Lymphoplasmacytic and eosinophilic enteritis (LEE) was ultimately diagnosed on intestinal biopsy histopathology based on the presence of small intestinal villous blunting and increased numbers of lymphocytes and eosinophils predominantly within the lamina propria. Numerous globule leukocytes were also noted on histopathology in 3 cases. All goats responded favorably to corticosteroid treatment with weight gain and resolution of diarrhea and clinicopathologic abnormalities. Relapses occurred, and complete cure was difficult to achieve. Reported in other species, this series describes the clinical presentation, diagnosis, and treatment of LEE in adult goats.
format	article
author	Mariya O. Pitel Meera C. Heller Jerry R. Roberson Erica C. McKenzie Devinn M. Sinnott Verena K. Affolter
author_facet	Mariya O. Pitel Meera C. Heller Jerry R. Roberson Erica C. McKenzie Devinn M. Sinnott Verena K. Affolter
author_sort	Mariya O. Pitel
title	Lymphoplasmacytic and eosinophilic enteritis with or without globule leukocyte hyperplasia in 4 goats
title_short	Lymphoplasmacytic and eosinophilic enteritis with or without globule leukocyte hyperplasia in 4 goats
title_full	Lymphoplasmacytic and eosinophilic enteritis with or without globule leukocyte hyperplasia in 4 goats
title_fullStr	Lymphoplasmacytic and eosinophilic enteritis with or without globule leukocyte hyperplasia in 4 goats
title_full_unstemmed	Lymphoplasmacytic and eosinophilic enteritis with or without globule leukocyte hyperplasia in 4 goats
title_sort	lymphoplasmacytic and eosinophilic enteritis with or without globule leukocyte hyperplasia in 4 goats
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/739d91eeac164b6393958ee0e326a50d
work_keys_str_mv	AT mariyaopitel lymphoplasmacyticandeosinophilicenteritiswithorwithoutglobuleleukocytehyperplasiain4goats AT meeracheller lymphoplasmacyticandeosinophilicenteritiswithorwithoutglobuleleukocytehyperplasiain4goats AT jerryrroberson lymphoplasmacyticandeosinophilicenteritiswithorwithoutglobuleleukocytehyperplasiain4goats AT ericacmckenzie lymphoplasmacyticandeosinophilicenteritiswithorwithoutglobuleleukocytehyperplasiain4goats AT devinnmsinnott lymphoplasmacyticandeosinophilicenteritiswithorwithoutglobuleleukocytehyperplasiain4goats AT verenakaffolter lymphoplasmacyticandeosinophilicenteritiswithorwithoutglobuleleukocytehyperplasiain4goats
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Lymphoplasmacytic and eosinophilic enteritis with or without globule leukocyte hyperplasia in 4 goats

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