Heterogeneity of tumor-infiltrating lymphocytes ascribed to local immune status rather than neoantigens by multi-omics analysis of glioblastoma multiforme
Abstract Hypothetically, intratumoral genomic heterogeneity has the potential to foster tumor-infiltrating lymphocyte (TIL) diversity; however, no study has directly tested this hypothesis by simultaneously investigating somatic mutations, TIL diversity, and immune response activity. Thus, we perfor...
Guardado en:
Autores principales: | Lin Feng, Haipeng Qian, Xuexin Yu, Kan Liu, Ting Xiao, Chengli Zhang, Manchao Kuang, Shujun Cheng, Xueji Li, Jinghai Wan, Kaitai Zhang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/73ac92b748db4882a71f36060f110928 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers
por: Daniel J. McGrail, et al.
Publicado: (2018) -
A novel signature for stratifying the molecular heterogeneity of the tissue-infiltrating T-cell receptor repertoire reflects gastric cancer prognosis
por: Manchao Kuang, et al.
Publicado: (2017) -
Network signatures of survival in glioblastoma multiforme.
por: Vishal N Patel, et al.
Publicado: (2013) -
A Multiparametric MR-Based RadioFusionOmics Model with Robust Capabilities of Differentiating Glioblastoma Multiforme from Solitary Brain Metastasis
por: Jialiang Wu, et al.
Publicado: (2021) -
The clinical significance of glutathione peroxidase 2 in glioblastoma multiforme
por: Guo Bangming, et al.
Publicado: (2021)