Mycobacterium Avium subsp. paratuberculosis isolates induce in vitro granuloma formation and show successful survival phenotype, common anti-inflammatory and antiapoptotic responses within ovine macrophages regardless of genotype or host of origin.

The analysis of the early macrophage responses, including bacterial growth within macrophages, represents a powerful tool to characterize the virulence of clinical isolates of Mycobcaterium avium susbp. paratuberculosis (Map). The present study represents the first assessment of the intracellular be...

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Autores principales: Naiara Abendaño, Lyudmila Tyukalova, Jesse F Barandika, Ana Balseiro, Iker A Sevilla, Joseba M Garrido, Ramon A Juste, Marta Alonso-Hearn
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/73af8eef7c09470a946114c710a27295
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