Ultrastructural analysis in yeast reveals a meiosis-specific actin-containing nuclear bundle

Using freeze-substitution electron microscopy, Takagi et al identify nuclear actin-containing bundles within meiotic yeast cells. These bundles are absent in stages other than meiosis I and in spo11 mutants defective in homologous recombination, allowing authors to speculate that these bundles may b...

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Auteurs principaux: Tomoko Takagi, Masako Osumi, Akira Shinohara
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/73b435b36c89414c9d6da09594e2ee67
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Résumé:Using freeze-substitution electron microscopy, Takagi et al identify nuclear actin-containing bundles within meiotic yeast cells. These bundles are absent in stages other than meiosis I and in spo11 mutants defective in homologous recombination, allowing authors to speculate that these bundles may be involved in meiotic chromosome movement or in protecting the nucleus from mechanical stress during cell division.