Inflammatory response of microglia to prions is controlled by sialylation of PrPSc

Abstract Neuroinflammation is recognized as one of the obligatory pathogenic features of neurodegenerative diseases including Alzheimer’s, Parkinson’s or prion diseases. In prion diseases, space and time correlations between deposition of disease-associated, pathogenic form of the prion protein or P...

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Bibliographic Details
Main Authors: Saurabh Srivastava, Elizaveta Katorcha, Natallia Makarava, James P. Barrett, David J. Loane, Ilia V. Baskakov
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/73bae15539c04cfe9bbcf492a6065dd6
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