NMDA receptor-dependent plasticity in the nucleus accumbens connects reward-predictive cues to approach responses

Conditioned stimuli elicit phasic changes in nucleus accumbens (NAc) firing that invigorate approach responses to predicted rewards. Here the authors show that NAc neurons acquire cue-evoked responses during learning as a result of excitatory plasticity within the NAc.

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Détails bibliographiques
Auteurs principaux:	Mercedes Vega-Villar, Jon C. Horvitz, Saleem M. Nicola
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/73c68206a0934f93bb5073cf24fe66a9
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id	oai:doaj.org-article:73c68206a0934f93bb5073cf24fe66a9
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spelling	oai:doaj.org-article:73c68206a0934f93bb5073cf24fe66a92021-12-02T14:39:19ZNMDA receptor-dependent plasticity in the nucleus accumbens connects reward-predictive cues to approach responses10.1038/s41467-019-12387-z2041-1723https://doaj.org/article/73c68206a0934f93bb5073cf24fe66a92019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12387-zhttps://doaj.org/toc/2041-1723Conditioned stimuli elicit phasic changes in nucleus accumbens (NAc) firing that invigorate approach responses to predicted rewards. Here the authors show that NAc neurons acquire cue-evoked responses during learning as a result of excitatory plasticity within the NAc.Mercedes Vega-VillarJon C. HorvitzSaleem M. NicolaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mercedes Vega-Villar Jon C. Horvitz Saleem M. Nicola NMDA receptor-dependent plasticity in the nucleus accumbens connects reward-predictive cues to approach responses
description	Conditioned stimuli elicit phasic changes in nucleus accumbens (NAc) firing that invigorate approach responses to predicted rewards. Here the authors show that NAc neurons acquire cue-evoked responses during learning as a result of excitatory plasticity within the NAc.
format	article
author	Mercedes Vega-Villar Jon C. Horvitz Saleem M. Nicola
author_facet	Mercedes Vega-Villar Jon C. Horvitz Saleem M. Nicola
author_sort	Mercedes Vega-Villar
title	NMDA receptor-dependent plasticity in the nucleus accumbens connects reward-predictive cues to approach responses
title_short	NMDA receptor-dependent plasticity in the nucleus accumbens connects reward-predictive cues to approach responses
title_full	NMDA receptor-dependent plasticity in the nucleus accumbens connects reward-predictive cues to approach responses
title_fullStr	NMDA receptor-dependent plasticity in the nucleus accumbens connects reward-predictive cues to approach responses
title_full_unstemmed	NMDA receptor-dependent plasticity in the nucleus accumbens connects reward-predictive cues to approach responses
title_sort	nmda receptor-dependent plasticity in the nucleus accumbens connects reward-predictive cues to approach responses
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/73c68206a0934f93bb5073cf24fe66a9
work_keys_str_mv	AT mercedesvegavillar nmdareceptordependentplasticityinthenucleusaccumbensconnectsrewardpredictivecuestoapproachresponses AT jonchorvitz nmdareceptordependentplasticityinthenucleusaccumbensconnectsrewardpredictivecuestoapproachresponses AT saleemmnicola nmdareceptordependentplasticityinthenucleusaccumbensconnectsrewardpredictivecuestoapproachresponses
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NMDA receptor-dependent plasticity in the nucleus accumbens connects reward-predictive cues to approach responses

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