Comprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients

The relationship between genomic alteration and immune context in non-small cell lung cancer (NSCLC) is complex. Here, the authors analyse the molecular and immunological landscape of 245 Chinese patients with NSCLC and find low immune infiltration correlates with genomic alterations.

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Autores principales: Xu-Chao Zhang, Jun Wang, Guo-Guang Shao, Qun Wang, Xiaotao Qu, Bo Wang, Christopher Moy, Yue Fan, Zayed Albertyn, Xiayu Huang, Jingyu Zhang, Yang Qiu, Suso Platero, Matthew V. Lorenzi, Enrique Zudaire, Jennifer Yang, Ying Cheng, Lin Xu, Yi-Long Wu
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/73c8286a0df443e885f70658074e7476
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spelling oai:doaj.org-article:73c8286a0df443e885f70658074e74762021-12-02T14:40:20ZComprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients10.1038/s41467-019-09762-12041-1723https://doaj.org/article/73c8286a0df443e885f70658074e74762019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09762-1https://doaj.org/toc/2041-1723The relationship between genomic alteration and immune context in non-small cell lung cancer (NSCLC) is complex. Here, the authors analyse the molecular and immunological landscape of 245 Chinese patients with NSCLC and find low immune infiltration correlates with genomic alterations.Xu-Chao ZhangJun WangGuo-Guang ShaoQun WangXiaotao QuBo WangChristopher MoyYue FanZayed AlbertynXiayu HuangJingyu ZhangYang QiuSuso PlateroMatthew V. LorenziEnrique ZudaireJennifer YangYing ChengLin XuYi-Long WuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xu-Chao Zhang
Jun Wang
Guo-Guang Shao
Qun Wang
Xiaotao Qu
Bo Wang
Christopher Moy
Yue Fan
Zayed Albertyn
Xiayu Huang
Jingyu Zhang
Yang Qiu
Suso Platero
Matthew V. Lorenzi
Enrique Zudaire
Jennifer Yang
Ying Cheng
Lin Xu
Yi-Long Wu
Comprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients
description The relationship between genomic alteration and immune context in non-small cell lung cancer (NSCLC) is complex. Here, the authors analyse the molecular and immunological landscape of 245 Chinese patients with NSCLC and find low immune infiltration correlates with genomic alterations.
format article
author Xu-Chao Zhang
Jun Wang
Guo-Guang Shao
Qun Wang
Xiaotao Qu
Bo Wang
Christopher Moy
Yue Fan
Zayed Albertyn
Xiayu Huang
Jingyu Zhang
Yang Qiu
Suso Platero
Matthew V. Lorenzi
Enrique Zudaire
Jennifer Yang
Ying Cheng
Lin Xu
Yi-Long Wu
author_facet Xu-Chao Zhang
Jun Wang
Guo-Guang Shao
Qun Wang
Xiaotao Qu
Bo Wang
Christopher Moy
Yue Fan
Zayed Albertyn
Xiayu Huang
Jingyu Zhang
Yang Qiu
Suso Platero
Matthew V. Lorenzi
Enrique Zudaire
Jennifer Yang
Ying Cheng
Lin Xu
Yi-Long Wu
author_sort Xu-Chao Zhang
title Comprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients
title_short Comprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients
title_full Comprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients
title_fullStr Comprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients
title_full_unstemmed Comprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients
title_sort comprehensive genomic and immunological characterization of chinese non-small cell lung cancer patients
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/73c8286a0df443e885f70658074e7476
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