Procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy

CRP and WBC are the most widely used markers of inflammation in veterinary clinical diagnosis. Also, PCT is a specific APP marker of bacterial diseases in humans. This study evaluated the levels of PCT, CRP and WBC during postoperative monitoring of bitches undergoing ovariohysterectomy. Thirteen ad...

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Autores principales:	Gürbüz Hasan Oğuz, Ulutaş Pınar Alkım
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2017
Materias:	procalcitonine c-reactive protein wbc dog ovariohysterectomy Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/73c97103c0284f458c75ec6743d5d9cf
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spelling	oai:doaj.org-article:73c97103c0284f458c75ec6743d5d9cf2021-11-17T21:27:51ZProcalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy1820-744810.1515/acve-2017-0012https://doaj.org/article/73c97103c0284f458c75ec6743d5d9cf2017-03-01T00:00:00Zhttps://doi.org/10.1515/acve-2017-0012https://doaj.org/toc/1820-7448CRP and WBC are the most widely used markers of inflammation in veterinary clinical diagnosis. Also, PCT is a specific APP marker of bacterial diseases in humans. This study evaluated the levels of PCT, CRP and WBC during postoperative monitoring of bitches undergoing ovariohysterectomy. Thirteen adult clinically healthy female crossbreed dogs aged between 7-24 months were used in the study. Ovariohysterectomy was performed via medial laparotomy using routine procedures. Blood samples were collected from the cephalic vein at 1, 4 and 7 days after surgery (post-op period). Mean serum concentration of PCT, CRP and WBC levels were increased after the surgery. CRP concentrations and WBC counts were increased significantly (p<0.001) on the first day after the operation and decreased to basal values. However, the PCT rise was not significant. CRP and WBC levels increased rapidly and decreased to normal values in dogs with ovariohysterectomy. CRP and WBC may be of help to determine the possible postoperative complications. Besides, aseptic surgical trauma did not affect PCT levels in dogs. Future studies are needed on canine PCT response focusing on specific bacterial infections.Gürbüz Hasan OğuzUlutaş Pınar AlkımSciendoarticleprocalcitoninec-reactive proteinwbcdogovariohysterectomyVeterinary medicineSF600-1100ENActa Veterinaria, Vol 67, Iss 1, Pp 131-136 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	procalcitonine c-reactive protein wbc dog ovariohysterectomy Veterinary medicine SF600-1100
spellingShingle	procalcitonine c-reactive protein wbc dog ovariohysterectomy Veterinary medicine SF600-1100 Gürbüz Hasan Oğuz Ulutaş Pınar Alkım Procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy
description	CRP and WBC are the most widely used markers of inflammation in veterinary clinical diagnosis. Also, PCT is a specific APP marker of bacterial diseases in humans. This study evaluated the levels of PCT, CRP and WBC during postoperative monitoring of bitches undergoing ovariohysterectomy. Thirteen adult clinically healthy female crossbreed dogs aged between 7-24 months were used in the study. Ovariohysterectomy was performed via medial laparotomy using routine procedures. Blood samples were collected from the cephalic vein at 1, 4 and 7 days after surgery (post-op period). Mean serum concentration of PCT, CRP and WBC levels were increased after the surgery. CRP concentrations and WBC counts were increased significantly (p<0.001) on the first day after the operation and decreased to basal values. However, the PCT rise was not significant. CRP and WBC levels increased rapidly and decreased to normal values in dogs with ovariohysterectomy. CRP and WBC may be of help to determine the possible postoperative complications. Besides, aseptic surgical trauma did not affect PCT levels in dogs. Future studies are needed on canine PCT response focusing on specific bacterial infections.
format	article
author	Gürbüz Hasan Oğuz Ulutaş Pınar Alkım
author_facet	Gürbüz Hasan Oğuz Ulutaş Pınar Alkım
author_sort	Gürbüz Hasan Oğuz
title	Procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy
title_short	Procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy
title_full	Procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy
title_fullStr	Procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy
title_full_unstemmed	Procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy
title_sort	procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy
publisher	Sciendo
publishDate	2017
url	https://doaj.org/article/73c97103c0284f458c75ec6743d5d9cf
work_keys_str_mv	AT gurbuzhasanoguz procalcitoninisnotamarkerofsterileinflammationindogsafterovariohysterectomy AT ulutaspınaralkım procalcitoninisnotamarkerofsterileinflammationindogsafterovariohysterectomy
_version_	1718425291894816768

Procalcitonin is not a marker of sterile inflammation in dogs after ovariohysterectomy

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