Thyroglossal duct cyst papillary thyroid cancer – the state of the art

Thyroglossal duct cyst is one of the most common congenital malformations in the neck area. The majority of cysts turn out to be benign tumors, however, 0.7-1.5 % of the remnants develop into carcinoma, with papillary thyroid cancer being the most frequent malignant neoplasm. The origin of the cance...

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Autores principales: Dabrowska Anna Maria, Dudka Jaroslaw
Formato: article
Lenguaje:EN
Publicado: Sciendo 2021
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Acceso en línea:https://doaj.org/article/73d2652d9e4c4d5ebf3450c24fb9a4d3
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spelling oai:doaj.org-article:73d2652d9e4c4d5ebf3450c24fb9a4d32021-12-05T14:11:06ZThyroglossal duct cyst papillary thyroid cancer – the state of the art2300-667610.2478/cipms-2021-0022https://doaj.org/article/73d2652d9e4c4d5ebf3450c24fb9a4d32021-09-01T00:00:00Zhttps://doi.org/10.2478/cipms-2021-0022https://doaj.org/toc/2300-6676Thyroglossal duct cyst is one of the most common congenital malformations in the neck area. The majority of cysts turn out to be benign tumors, however, 0.7-1.5 % of the remnants develop into carcinoma, with papillary thyroid cancer being the most frequent malignant neoplasm. The origin of the cancer has not been clearly established so far. Typically, thyroglossal duct cyst cancer is an enlarging flexible midline or slightly lateral neck mass, most often without other worrisome symptoms. The proper diagnosis can be difficult due to the rare prevalence of thyroglossal duct cyst papillary thyroid carcinoma, as well as a lack of strongly typical features distinguishing benign and malignant lesions before surgery. Thus, diagnosis is usually made postoperatively just after histopathological examination of a resected cyst. However, there are diagnostic procedures that should be considered before the surgery that may be helpful in making a proper diagnosis. These include fine-needle aspiration biopsy, computed tomography or magnetic resonance imaging. Moreover, there are some characteristics revealed through clinical and ultrasound examination that may suggest the presence of such cancer. While the Sistrunk procedure is often considered adequate, currently, there is no clear consensus about concurrent thyroidectomy or radioiodine therapy. In the article, we sum up the preoperative suggestive factors of cancer, as well as the proposed indications that can be helpful in deciding on the extent of surgery and further management.Dabrowska Anna MariaDudka JaroslawSciendoarticlethyroglossal duct cystthyroglossal duct cyst cancerectopic papillary thyroid cancersistrunk surgeryMedicineRENCurrent Issues in Pharmacy and Medical Sciences, Vol 34, Iss 3, Pp 160-163 (2021)
institution DOAJ
collection DOAJ
language EN
topic thyroglossal duct cyst
thyroglossal duct cyst cancer
ectopic papillary thyroid cancer
sistrunk surgery
Medicine
R
spellingShingle thyroglossal duct cyst
thyroglossal duct cyst cancer
ectopic papillary thyroid cancer
sistrunk surgery
Medicine
R
Dabrowska Anna Maria
Dudka Jaroslaw
Thyroglossal duct cyst papillary thyroid cancer – the state of the art
description Thyroglossal duct cyst is one of the most common congenital malformations in the neck area. The majority of cysts turn out to be benign tumors, however, 0.7-1.5 % of the remnants develop into carcinoma, with papillary thyroid cancer being the most frequent malignant neoplasm. The origin of the cancer has not been clearly established so far. Typically, thyroglossal duct cyst cancer is an enlarging flexible midline or slightly lateral neck mass, most often without other worrisome symptoms. The proper diagnosis can be difficult due to the rare prevalence of thyroglossal duct cyst papillary thyroid carcinoma, as well as a lack of strongly typical features distinguishing benign and malignant lesions before surgery. Thus, diagnosis is usually made postoperatively just after histopathological examination of a resected cyst. However, there are diagnostic procedures that should be considered before the surgery that may be helpful in making a proper diagnosis. These include fine-needle aspiration biopsy, computed tomography or magnetic resonance imaging. Moreover, there are some characteristics revealed through clinical and ultrasound examination that may suggest the presence of such cancer. While the Sistrunk procedure is often considered adequate, currently, there is no clear consensus about concurrent thyroidectomy or radioiodine therapy. In the article, we sum up the preoperative suggestive factors of cancer, as well as the proposed indications that can be helpful in deciding on the extent of surgery and further management.
format article
author Dabrowska Anna Maria
Dudka Jaroslaw
author_facet Dabrowska Anna Maria
Dudka Jaroslaw
author_sort Dabrowska Anna Maria
title Thyroglossal duct cyst papillary thyroid cancer – the state of the art
title_short Thyroglossal duct cyst papillary thyroid cancer – the state of the art
title_full Thyroglossal duct cyst papillary thyroid cancer – the state of the art
title_fullStr Thyroglossal duct cyst papillary thyroid cancer – the state of the art
title_full_unstemmed Thyroglossal duct cyst papillary thyroid cancer – the state of the art
title_sort thyroglossal duct cyst papillary thyroid cancer – the state of the art
publisher Sciendo
publishDate 2021
url https://doaj.org/article/73d2652d9e4c4d5ebf3450c24fb9a4d3
work_keys_str_mv AT dabrowskaannamaria thyroglossalductcystpapillarythyroidcancerthestateoftheart
AT dudkajaroslaw thyroglossalductcystpapillarythyroidcancerthestateoftheart
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