EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion

EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion

Abstract Enhancer of zeste homolog 2 (EZH2) is often increased in malignant tumors and is involved in metastasis. EZH2 silences gene expression by tri-methylating the lysine 27 residue of histone H3 (H3K27me3). However, the mechanism underlying EZH2 promotion of ovarian cancer metastasis remains elu...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Xiaoqing Yi, Jianfeng Guo, Jing Guo, Si Sun, Ping Yang, Junjie Wang, Yuan Li, Lisha Xie, Jing Cai, Zehua Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/73dc2287caf146d6a51c6c9b7f2edf27
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares