Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission

Gephyrin is a cytoplasmic scaffolding protein that selectively forms postsynaptic scaffolds at GABAergic and glycinergic synapses. Here the authors characterize regulatory mechanisms determining gephyrin scaffolding and GABAA receptor synaptic transmission that involve acetylation, SUMOylation and p...

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Autores principales:	Himanish Ghosh, Luca Auguadri, Sereina Battaglia, Zahra Simone Thirouin, Khaled Zemoura, Simon Messner, Mario A. Acuña, Hendrik Wildner, Gonzalo E. Yévenes, Andrea Dieter, Hiroshi Kawasaki, Michael O. Hottiger, Hanns Ulrich Zeilhofer, Jean-Marc Fritschy, Shiva K. Tyagarajan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/73ddc1c5e39d47848b61414b2085adaa
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spelling	oai:doaj.org-article:73ddc1c5e39d47848b61414b2085adaa2021-12-02T15:34:54ZSeveral posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission10.1038/ncomms133652041-1723https://doaj.org/article/73ddc1c5e39d47848b61414b2085adaa2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13365https://doaj.org/toc/2041-1723Gephyrin is a cytoplasmic scaffolding protein that selectively forms postsynaptic scaffolds at GABAergic and glycinergic synapses. Here the authors characterize regulatory mechanisms determining gephyrin scaffolding and GABAA receptor synaptic transmission that involve acetylation, SUMOylation and phosphorylation.Himanish GhoshLuca AuguadriSereina BattagliaZahra Simone ThirouinKhaled ZemouraSimon MessnerMario A. AcuñaHendrik WildnerGonzalo E. YévenesAndrea DieterHiroshi KawasakiMichael O. HottigerHanns Ulrich ZeilhoferJean-Marc FritschyShiva K. TyagarajanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Himanish Ghosh Luca Auguadri Sereina Battaglia Zahra Simone Thirouin Khaled Zemoura Simon Messner Mario A. Acuña Hendrik Wildner Gonzalo E. Yévenes Andrea Dieter Hiroshi Kawasaki Michael O. Hottiger Hanns Ulrich Zeilhofer Jean-Marc Fritschy Shiva K. Tyagarajan Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission
description	Gephyrin is a cytoplasmic scaffolding protein that selectively forms postsynaptic scaffolds at GABAergic and glycinergic synapses. Here the authors characterize regulatory mechanisms determining gephyrin scaffolding and GABAA receptor synaptic transmission that involve acetylation, SUMOylation and phosphorylation.
format	article
author	Himanish Ghosh Luca Auguadri Sereina Battaglia Zahra Simone Thirouin Khaled Zemoura Simon Messner Mario A. Acuña Hendrik Wildner Gonzalo E. Yévenes Andrea Dieter Hiroshi Kawasaki Michael O. Hottiger Hanns Ulrich Zeilhofer Jean-Marc Fritschy Shiva K. Tyagarajan
author_facet	Himanish Ghosh Luca Auguadri Sereina Battaglia Zahra Simone Thirouin Khaled Zemoura Simon Messner Mario A. Acuña Hendrik Wildner Gonzalo E. Yévenes Andrea Dieter Hiroshi Kawasaki Michael O. Hottiger Hanns Ulrich Zeilhofer Jean-Marc Fritschy Shiva K. Tyagarajan
author_sort	Himanish Ghosh
title	Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission
title_short	Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission
title_full	Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission
title_fullStr	Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission
title_full_unstemmed	Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission
title_sort	several posttranslational modifications act in concert to regulate gephyrin scaffolding and gabaergic transmission
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/73ddc1c5e39d47848b61414b2085adaa
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Several posttranslational modifications act in concert to regulate gephyrin scaffolding and GABAergic transmission

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