Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission.
Efficient HTLV-1 viral transmission occurs through cell-to-cell contacts. The Tax viral transcriptional activator protein facilitates this process. Using a comparative transcriptomic analysis, we recently identified a series of genes up-regulated in HTLV-1 Tax expressing T-lymphocytes. We focused ou...
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Autores principales: | Sébastien A Chevalier, Jocelyn Turpin, Anne Cachat, Philippe V Afonso, Antoine Gessain, John N Brady, Cynthia A Pise-Masison, Renaud Mahieux |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/73e1715ede6243709166bd62b0e813e8 |
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