Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission.

Efficient HTLV-1 viral transmission occurs through cell-to-cell contacts. The Tax viral transcriptional activator protein facilitates this process. Using a comparative transcriptomic analysis, we recently identified a series of genes up-regulated in HTLV-1 Tax expressing T-lymphocytes. We focused ou...

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Autores principales: Sébastien A Chevalier, Jocelyn Turpin, Anne Cachat, Philippe V Afonso, Antoine Gessain, John N Brady, Cynthia A Pise-Masison, Renaud Mahieux
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/73e1715ede6243709166bd62b0e813e8
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