Severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–2013

Abstract We aimed to evaluate the risk of coronary heart disease (CHD) according to dental caries status in middle-aged patients using a population-based cohort database containing medical/dental claims, health examination, and death records in the Republic of Korea. A total of 234,597 patients were...

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Autores principales:	Kyuwoong Kim, Seulggie Choi, Jooyoung Chang, Sung Min Kim, Seon Jip Kim, Ryan Jin-Young Kim, Hyun-Jae Cho, Sang Min Park
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/73e4495bb5aa4ad7a0734e229b24ced2
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spelling	oai:doaj.org-article:73e4495bb5aa4ad7a0734e229b24ced22021-12-02T15:07:55ZSeverity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–201310.1038/s41598-019-47029-32045-2322https://doaj.org/article/73e4495bb5aa4ad7a0734e229b24ced22019-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-019-47029-3https://doaj.org/toc/2045-2322Abstract We aimed to evaluate the risk of coronary heart disease (CHD) according to dental caries status in middle-aged patients using a population-based cohort database containing medical/dental claims, health examination, and death records in the Republic of Korea. A total of 234,597 patients were identified in the database who were without history of cardiovascular disease, including 104,638 patients without dental caries, 41,696 with incipient/moderate stage dental caries, and 88,262 advanced/severe dental caries. We used Cox proportional hazards model adjusted for sociodemographic, lifestyle, and medical characteristics to compute hazard ratio (HR) and 95% confidence intervals (95% CI) for CHD according to severity of dental caries. During 1,491,190 person-years of follow-up, there were a total of 6,015 CHD events. After adjustment for potential confounders, patients in the highest quartile of outpatient visits for advanced/severe stage dental caries was associated with an increase in CHD risk (HR = 1.13; 95% CI: 1.04–1.22) as compared with patients without dental caries. When the analysis was restricted to the patients with advanced/severe dental caries, dose-response relationship between number of outpatient visits for dental caries and risk of CHD was observed (P trend : <0.001). Prevention and control of dental caries might be worth promoting in clinical practice to prevent CHD.Kyuwoong KimSeulggie ChoiJooyoung ChangSung Min KimSeon Jip KimRyan Jin-Young KimHyun-Jae ChoSang Min ParkNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kyuwoong Kim Seulggie Choi Jooyoung Chang Sung Min Kim Seon Jip Kim Ryan Jin-Young Kim Hyun-Jae Cho Sang Min Park Severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–2013
description	Abstract We aimed to evaluate the risk of coronary heart disease (CHD) according to dental caries status in middle-aged patients using a population-based cohort database containing medical/dental claims, health examination, and death records in the Republic of Korea. A total of 234,597 patients were identified in the database who were without history of cardiovascular disease, including 104,638 patients without dental caries, 41,696 with incipient/moderate stage dental caries, and 88,262 advanced/severe dental caries. We used Cox proportional hazards model adjusted for sociodemographic, lifestyle, and medical characteristics to compute hazard ratio (HR) and 95% confidence intervals (95% CI) for CHD according to severity of dental caries. During 1,491,190 person-years of follow-up, there were a total of 6,015 CHD events. After adjustment for potential confounders, patients in the highest quartile of outpatient visits for advanced/severe stage dental caries was associated with an increase in CHD risk (HR = 1.13; 95% CI: 1.04–1.22) as compared with patients without dental caries. When the analysis was restricted to the patients with advanced/severe dental caries, dose-response relationship between number of outpatient visits for dental caries and risk of CHD was observed (P trend : <0.001). Prevention and control of dental caries might be worth promoting in clinical practice to prevent CHD.
format	article
author	Kyuwoong Kim Seulggie Choi Jooyoung Chang Sung Min Kim Seon Jip Kim Ryan Jin-Young Kim Hyun-Jae Cho Sang Min Park
author_facet	Kyuwoong Kim Seulggie Choi Jooyoung Chang Sung Min Kim Seon Jip Kim Ryan Jin-Young Kim Hyun-Jae Cho Sang Min Park
author_sort	Kyuwoong Kim
title	Severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–2013
title_short	Severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–2013
title_full	Severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–2013
title_fullStr	Severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–2013
title_full_unstemmed	Severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–2013
title_sort	severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of korean adults, 2002–2013
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/73e4495bb5aa4ad7a0734e229b24ced2
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Severity of dental caries and risk of coronary heart disease in middle-aged men and women: a population-based cohort study of Korean adults, 2002–2013

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