The complete local genotype–phenotype landscape for the alternative splicing of a human exon

Genotype–phenotype landscapes are an important characteristic for understanding the evolution of traits. Here the authors construct the local landscape for the alternative splicing of FAS/CD95 exon 6, revealing the regulation of splicing and the evolution of regulatory information between species.

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Autores principales:	Philippe Julien, Belén Miñana, Pablo Baeza-Centurion, Juan Valcárcel, Ben Lehner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/73ea67a542874df4ab8caf4583215cb2
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spelling	oai:doaj.org-article:73ea67a542874df4ab8caf4583215cb22021-12-02T17:31:18ZThe complete local genotype–phenotype landscape for the alternative splicing of a human exon10.1038/ncomms115582041-1723https://doaj.org/article/73ea67a542874df4ab8caf4583215cb22016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11558https://doaj.org/toc/2041-1723Genotype–phenotype landscapes are an important characteristic for understanding the evolution of traits. Here the authors construct the local landscape for the alternative splicing of FAS/CD95 exon 6, revealing the regulation of splicing and the evolution of regulatory information between species.Philippe JulienBelén MiñanaPablo Baeza-CenturionJuan ValcárcelBen LehnerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Philippe Julien Belén Miñana Pablo Baeza-Centurion Juan Valcárcel Ben Lehner The complete local genotype–phenotype landscape for the alternative splicing of a human exon
description	Genotype–phenotype landscapes are an important characteristic for understanding the evolution of traits. Here the authors construct the local landscape for the alternative splicing of FAS/CD95 exon 6, revealing the regulation of splicing and the evolution of regulatory information between species.
format	article
author	Philippe Julien Belén Miñana Pablo Baeza-Centurion Juan Valcárcel Ben Lehner
author_facet	Philippe Julien Belén Miñana Pablo Baeza-Centurion Juan Valcárcel Ben Lehner
author_sort	Philippe Julien
title	The complete local genotype–phenotype landscape for the alternative splicing of a human exon
title_short	The complete local genotype–phenotype landscape for the alternative splicing of a human exon
title_full	The complete local genotype–phenotype landscape for the alternative splicing of a human exon
title_fullStr	The complete local genotype–phenotype landscape for the alternative splicing of a human exon
title_full_unstemmed	The complete local genotype–phenotype landscape for the alternative splicing of a human exon
title_sort	complete local genotype–phenotype landscape for the alternative splicing of a human exon
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/73ea67a542874df4ab8caf4583215cb2
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The complete local genotype–phenotype landscape for the alternative splicing of a human exon

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