Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs
Preclinical studies have shown that negative pressure ventilation ex situ lung perfusion results in less ventilator-induced lung injury compared to positive pressure ventilation of donor lungs during transplantation procedures. Here the authors perform a single-arm clinical trial with 12 participant...
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Nature Portfolio
2020
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oai:doaj.org-article:73ef3d3b5efa447db5d60d62e08f91372021-12-02T14:41:23ZClinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs10.1038/s41467-020-19581-42041-1723https://doaj.org/article/73ef3d3b5efa447db5d60d62e08f91372020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19581-4https://doaj.org/toc/2041-1723Preclinical studies have shown that negative pressure ventilation ex situ lung perfusion results in less ventilator-induced lung injury compared to positive pressure ventilation of donor lungs during transplantation procedures. Here the authors perform a single-arm clinical trial with 12 participants to study patient survival and primary graft dysfunction with ex situ lung perfusion.Max T. BuchkoNasim BoroumandJeffrey C. ChengAlim HirjiKieran HalloranDarren H. FreedJayan NagendranNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-5 (2020) |
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Science Q Max T. Buchko Nasim Boroumand Jeffrey C. Cheng Alim Hirji Kieran Halloran Darren H. Freed Jayan Nagendran Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs |
description |
Preclinical studies have shown that negative pressure ventilation ex situ lung perfusion results in less ventilator-induced lung injury compared to positive pressure ventilation of donor lungs during transplantation procedures. Here the authors perform a single-arm clinical trial with 12 participants to study patient survival and primary graft dysfunction with ex situ lung perfusion. |
format |
article |
author |
Max T. Buchko Nasim Boroumand Jeffrey C. Cheng Alim Hirji Kieran Halloran Darren H. Freed Jayan Nagendran |
author_facet |
Max T. Buchko Nasim Boroumand Jeffrey C. Cheng Alim Hirji Kieran Halloran Darren H. Freed Jayan Nagendran |
author_sort |
Max T. Buchko |
title |
Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs |
title_short |
Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs |
title_full |
Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs |
title_fullStr |
Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs |
title_full_unstemmed |
Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs |
title_sort |
clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/73ef3d3b5efa447db5d60d62e08f9137 |
work_keys_str_mv |
AT maxtbuchko clinicaltransplantationusingnegativepressureventilationexsitulungperfusionwithextendedcriteriadonorlungs AT nasimboroumand clinicaltransplantationusingnegativepressureventilationexsitulungperfusionwithextendedcriteriadonorlungs AT jeffreyccheng clinicaltransplantationusingnegativepressureventilationexsitulungperfusionwithextendedcriteriadonorlungs AT alimhirji clinicaltransplantationusingnegativepressureventilationexsitulungperfusionwithextendedcriteriadonorlungs AT kieranhalloran clinicaltransplantationusingnegativepressureventilationexsitulungperfusionwithextendedcriteriadonorlungs AT darrenhfreed clinicaltransplantationusingnegativepressureventilationexsitulungperfusionwithextendedcriteriadonorlungs AT jayannagendran clinicaltransplantationusingnegativepressureventilationexsitulungperfusionwithextendedcriteriadonorlungs |
_version_ |
1718389877956935680 |