Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs

Preclinical studies have shown that negative pressure ventilation ex situ lung perfusion results in less ventilator-induced lung injury compared to positive pressure ventilation of donor lungs during transplantation procedures. Here the authors perform a single-arm clinical trial with 12 participant...

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Autores principales: Max T. Buchko, Nasim Boroumand, Jeffrey C. Cheng, Alim Hirji, Kieran Halloran, Darren H. Freed, Jayan Nagendran
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/73ef3d3b5efa447db5d60d62e08f9137
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spelling oai:doaj.org-article:73ef3d3b5efa447db5d60d62e08f91372021-12-02T14:41:23ZClinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs10.1038/s41467-020-19581-42041-1723https://doaj.org/article/73ef3d3b5efa447db5d60d62e08f91372020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19581-4https://doaj.org/toc/2041-1723Preclinical studies have shown that negative pressure ventilation ex situ lung perfusion results in less ventilator-induced lung injury compared to positive pressure ventilation of donor lungs during transplantation procedures. Here the authors perform a single-arm clinical trial with 12 participants to study patient survival and primary graft dysfunction with ex situ lung perfusion.Max T. BuchkoNasim BoroumandJeffrey C. ChengAlim HirjiKieran HalloranDarren H. FreedJayan NagendranNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-5 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Max T. Buchko
Nasim Boroumand
Jeffrey C. Cheng
Alim Hirji
Kieran Halloran
Darren H. Freed
Jayan Nagendran
Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs
description Preclinical studies have shown that negative pressure ventilation ex situ lung perfusion results in less ventilator-induced lung injury compared to positive pressure ventilation of donor lungs during transplantation procedures. Here the authors perform a single-arm clinical trial with 12 participants to study patient survival and primary graft dysfunction with ex situ lung perfusion.
format article
author Max T. Buchko
Nasim Boroumand
Jeffrey C. Cheng
Alim Hirji
Kieran Halloran
Darren H. Freed
Jayan Nagendran
author_facet Max T. Buchko
Nasim Boroumand
Jeffrey C. Cheng
Alim Hirji
Kieran Halloran
Darren H. Freed
Jayan Nagendran
author_sort Max T. Buchko
title Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs
title_short Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs
title_full Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs
title_fullStr Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs
title_full_unstemmed Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs
title_sort clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/73ef3d3b5efa447db5d60d62e08f9137
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AT jeffreyccheng clinicaltransplantationusingnegativepressureventilationexsitulungperfusionwithextendedcriteriadonorlungs
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