CoA synthase regulates mitotic fidelity via CBP-mediated acetylation

The temporal activation of kinases and timely ubiquitin-mediated degradation is central to faithful mitosis. Here the authors show that acetylation controlled by Coenzyme A synthase (COASY) and acetyltransferase CBP constitutes a mechanism that ensures faithful mitosis.

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Autores principales: Chao-Chieh Lin, Mayumi Kitagawa, Xiaohu Tang, Ming-Hsin Hou, Jianli Wu, Dan Chen Qu, Vinayaka Srinivas, Xiaojing Liu, J. Will Thompson, Bernard Mathey-Prevot, Tso-Pang Yao, Sang Hyun Lee, Jen-Tsan Chi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/740481a53a4a45c9a625d4373dbffcb2
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spelling oai:doaj.org-article:740481a53a4a45c9a625d4373dbffcb22021-12-02T15:34:44ZCoA synthase regulates mitotic fidelity via CBP-mediated acetylation10.1038/s41467-018-03422-62041-1723https://doaj.org/article/740481a53a4a45c9a625d4373dbffcb22018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03422-6https://doaj.org/toc/2041-1723The temporal activation of kinases and timely ubiquitin-mediated degradation is central to faithful mitosis. Here the authors show that acetylation controlled by Coenzyme A synthase (COASY) and acetyltransferase CBP constitutes a mechanism that ensures faithful mitosis.Chao-Chieh LinMayumi KitagawaXiaohu TangMing-Hsin HouJianli WuDan Chen QuVinayaka SrinivasXiaojing LiuJ. Will ThompsonBernard Mathey-PrevotTso-Pang YaoSang Hyun LeeJen-Tsan ChiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chao-Chieh Lin
Mayumi Kitagawa
Xiaohu Tang
Ming-Hsin Hou
Jianli Wu
Dan Chen Qu
Vinayaka Srinivas
Xiaojing Liu
J. Will Thompson
Bernard Mathey-Prevot
Tso-Pang Yao
Sang Hyun Lee
Jen-Tsan Chi
CoA synthase regulates mitotic fidelity via CBP-mediated acetylation
description The temporal activation of kinases and timely ubiquitin-mediated degradation is central to faithful mitosis. Here the authors show that acetylation controlled by Coenzyme A synthase (COASY) and acetyltransferase CBP constitutes a mechanism that ensures faithful mitosis.
format article
author Chao-Chieh Lin
Mayumi Kitagawa
Xiaohu Tang
Ming-Hsin Hou
Jianli Wu
Dan Chen Qu
Vinayaka Srinivas
Xiaojing Liu
J. Will Thompson
Bernard Mathey-Prevot
Tso-Pang Yao
Sang Hyun Lee
Jen-Tsan Chi
author_facet Chao-Chieh Lin
Mayumi Kitagawa
Xiaohu Tang
Ming-Hsin Hou
Jianli Wu
Dan Chen Qu
Vinayaka Srinivas
Xiaojing Liu
J. Will Thompson
Bernard Mathey-Prevot
Tso-Pang Yao
Sang Hyun Lee
Jen-Tsan Chi
author_sort Chao-Chieh Lin
title CoA synthase regulates mitotic fidelity via CBP-mediated acetylation
title_short CoA synthase regulates mitotic fidelity via CBP-mediated acetylation
title_full CoA synthase regulates mitotic fidelity via CBP-mediated acetylation
title_fullStr CoA synthase regulates mitotic fidelity via CBP-mediated acetylation
title_full_unstemmed CoA synthase regulates mitotic fidelity via CBP-mediated acetylation
title_sort coa synthase regulates mitotic fidelity via cbp-mediated acetylation
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/740481a53a4a45c9a625d4373dbffcb2
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