CoA synthase regulates mitotic fidelity via CBP-mediated acetylation
The temporal activation of kinases and timely ubiquitin-mediated degradation is central to faithful mitosis. Here the authors show that acetylation controlled by Coenzyme A synthase (COASY) and acetyltransferase CBP constitutes a mechanism that ensures faithful mitosis.
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Nature Portfolio
2018
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oai:doaj.org-article:740481a53a4a45c9a625d4373dbffcb22021-12-02T15:34:44ZCoA synthase regulates mitotic fidelity via CBP-mediated acetylation10.1038/s41467-018-03422-62041-1723https://doaj.org/article/740481a53a4a45c9a625d4373dbffcb22018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03422-6https://doaj.org/toc/2041-1723The temporal activation of kinases and timely ubiquitin-mediated degradation is central to faithful mitosis. Here the authors show that acetylation controlled by Coenzyme A synthase (COASY) and acetyltransferase CBP constitutes a mechanism that ensures faithful mitosis.Chao-Chieh LinMayumi KitagawaXiaohu TangMing-Hsin HouJianli WuDan Chen QuVinayaka SrinivasXiaojing LiuJ. Will ThompsonBernard Mathey-PrevotTso-Pang YaoSang Hyun LeeJen-Tsan ChiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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DOAJ |
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EN |
topic |
Science Q |
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Science Q Chao-Chieh Lin Mayumi Kitagawa Xiaohu Tang Ming-Hsin Hou Jianli Wu Dan Chen Qu Vinayaka Srinivas Xiaojing Liu J. Will Thompson Bernard Mathey-Prevot Tso-Pang Yao Sang Hyun Lee Jen-Tsan Chi CoA synthase regulates mitotic fidelity via CBP-mediated acetylation |
description |
The temporal activation of kinases and timely ubiquitin-mediated degradation is central to faithful mitosis. Here the authors show that acetylation controlled by Coenzyme A synthase (COASY) and acetyltransferase CBP constitutes a mechanism that ensures faithful mitosis. |
format |
article |
author |
Chao-Chieh Lin Mayumi Kitagawa Xiaohu Tang Ming-Hsin Hou Jianli Wu Dan Chen Qu Vinayaka Srinivas Xiaojing Liu J. Will Thompson Bernard Mathey-Prevot Tso-Pang Yao Sang Hyun Lee Jen-Tsan Chi |
author_facet |
Chao-Chieh Lin Mayumi Kitagawa Xiaohu Tang Ming-Hsin Hou Jianli Wu Dan Chen Qu Vinayaka Srinivas Xiaojing Liu J. Will Thompson Bernard Mathey-Prevot Tso-Pang Yao Sang Hyun Lee Jen-Tsan Chi |
author_sort |
Chao-Chieh Lin |
title |
CoA synthase regulates mitotic fidelity via CBP-mediated acetylation |
title_short |
CoA synthase regulates mitotic fidelity via CBP-mediated acetylation |
title_full |
CoA synthase regulates mitotic fidelity via CBP-mediated acetylation |
title_fullStr |
CoA synthase regulates mitotic fidelity via CBP-mediated acetylation |
title_full_unstemmed |
CoA synthase regulates mitotic fidelity via CBP-mediated acetylation |
title_sort |
coa synthase regulates mitotic fidelity via cbp-mediated acetylation |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/740481a53a4a45c9a625d4373dbffcb2 |
work_keys_str_mv |
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1718386788414783488 |