The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding

The sperm-specific solute carrier SLC9C1 is a phylogenetic chimaera that carries a voltage-sensing (VSD) and a cyclic nucleotide-binding domain (CNBD). Here authors show by electrophysiology and fluorimetry that SLC9C1 is a genuine Na+/H+ exchanger gated by voltage and cAMP.

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Autores principales:	F. Windler, W. Bönigk, H. G. Körschen, E. Grahn, T. Strünker, R. Seifert, U. B. Kaupp
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/742306b5d7b749e79ce281e48097bba0
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spelling	oai:doaj.org-article:742306b5d7b749e79ce281e48097bba02021-12-02T17:32:33ZThe solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding10.1038/s41467-018-05253-x2041-1723https://doaj.org/article/742306b5d7b749e79ce281e48097bba02018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05253-xhttps://doaj.org/toc/2041-1723The sperm-specific solute carrier SLC9C1 is a phylogenetic chimaera that carries a voltage-sensing (VSD) and a cyclic nucleotide-binding domain (CNBD). Here authors show by electrophysiology and fluorimetry that SLC9C1 is a genuine Na+/H+ exchanger gated by voltage and cAMP.F. WindlerW. BönigkH. G. KörschenE. GrahnT. StrünkerR. SeifertU. B. KauppNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q F. Windler W. Bönigk H. G. Körschen E. Grahn T. Strünker R. Seifert U. B. Kaupp The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding
description	The sperm-specific solute carrier SLC9C1 is a phylogenetic chimaera that carries a voltage-sensing (VSD) and a cyclic nucleotide-binding domain (CNBD). Here authors show by electrophysiology and fluorimetry that SLC9C1 is a genuine Na+/H+ exchanger gated by voltage and cAMP.
format	article
author	F. Windler W. Bönigk H. G. Körschen E. Grahn T. Strünker R. Seifert U. B. Kaupp
author_facet	F. Windler W. Bönigk H. G. Körschen E. Grahn T. Strünker R. Seifert U. B. Kaupp
author_sort	F. Windler
title	The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding
title_short	The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding
title_full	The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding
title_fullStr	The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding
title_full_unstemmed	The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding
title_sort	solute carrier slc9c1 is a na+/h+-exchanger gated by an s4-type voltage-sensor and cyclic-nucleotide binding
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/742306b5d7b749e79ce281e48097bba0
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The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding

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