Aptamer-based optical manipulation of protein subcellular localization in cells
Optogenetic manipulation of protein localisation in cells involves the creation of fusions that can influence activity. Here the authors develop a near-infrared light-responsive aptamer-based system to regulate the nuclear-cytoplasmic shuttling of NF-κB subunit RelA.
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Auteurs principaux: | Sitao Xie, Yulin Du, Yu Zhang, Zhimin Wang, Dailiang Zhang, Lei He, Liping Qiu, Jianhui Jiang, Weihong Tan |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
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Accès en ligne: | https://doaj.org/article/742312874b8542a78c33a7f1a79ba1ad |
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