Immunomodulatory effects of Echinacea and Pelargonium on the innate and adoptive immunity in calves

Immunomodulatory effects of Echinacea purpurae and Pelargonium sidoides in calves were investigated. Sixty 25-day-old nonvaccinated calves living in integrated farm unit were randomly selected and were divided into 5 treatment groups consisting of 12 calves each; 4 groups were receiving different am...

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Autores principales:	Cuneyt Seckin, Gamze Alpun Kalayci, Nuri Turan, Aysun Yilmaz, Utku Y. Cizmecigil, Ozge Aydin, Juergen A. Richt, Huseyin Yilmaz
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2018
Materias:	calf immunity cytokine igg γ-interferon pcr echinacea pelargonium Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/742e2f9364424447883c16f6e7a09011
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spelling	oai:doaj.org-article:742e2f9364424447883c16f6e7a090112021-11-26T11:19:46ZImmunomodulatory effects of Echinacea and Pelargonium on the innate and adoptive immunity in calves0954-01051465-344310.1080/09540105.2018.1444738https://doaj.org/article/742e2f9364424447883c16f6e7a090112018-01-01T00:00:00Zhttp://dx.doi.org/10.1080/09540105.2018.1444738https://doaj.org/toc/0954-0105https://doaj.org/toc/1465-3443Immunomodulatory effects of Echinacea purpurae and Pelargonium sidoides in calves were investigated. Sixty 25-day-old nonvaccinated calves living in integrated farm unit were randomly selected and were divided into 5 treatment groups consisting of 12 calves each; 4 groups were receiving different amounts and/or times of Echinacea and Pelargonium and the control group received placebo. Blood levels of γ-interferon, cytokine gene expression, lactoferrin and total IgG were analysed on days 0, 9, and 30. When levels for total IgG, γ-interferon, mRNAs for the γ-interferon, IL-1-β, IL-4 and the tumour necrosis factor-α genes were compared from days 0 to 9 post-treatment, significant differences were found between treated and non-treated calves using various amounts of Echinacea and Pelargonium; a doses of 250 mg Echinacea and 62.5 mg Pelargonium for 5 days seems to be ideal. Echinacea purpurae and Pelargonium sidoides are able to modulate immune functions in calves.Cuneyt SeckinGamze Alpun KalayciNuri TuranAysun YilmazUtku Y. CizmecigilOzge AydinJuergen A. RichtHuseyin YilmazTaylor & Francis Grouparticlecalfimmunitycytokineiggγ-interferonpcrechinaceapelargoniumAgriculture (General)S1-972Immunologic diseases. AllergyRC581-607ENFood and Agricultural Immunology, Vol 29, Iss 1, Pp 744-761 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	calf immunity cytokine igg γ-interferon pcr echinacea pelargonium Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607
spellingShingle	calf immunity cytokine igg γ-interferon pcr echinacea pelargonium Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607 Cuneyt Seckin Gamze Alpun Kalayci Nuri Turan Aysun Yilmaz Utku Y. Cizmecigil Ozge Aydin Juergen A. Richt Huseyin Yilmaz Immunomodulatory effects of Echinacea and Pelargonium on the innate and adoptive immunity in calves
description	Immunomodulatory effects of Echinacea purpurae and Pelargonium sidoides in calves were investigated. Sixty 25-day-old nonvaccinated calves living in integrated farm unit were randomly selected and were divided into 5 treatment groups consisting of 12 calves each; 4 groups were receiving different amounts and/or times of Echinacea and Pelargonium and the control group received placebo. Blood levels of γ-interferon, cytokine gene expression, lactoferrin and total IgG were analysed on days 0, 9, and 30. When levels for total IgG, γ-interferon, mRNAs for the γ-interferon, IL-1-β, IL-4 and the tumour necrosis factor-α genes were compared from days 0 to 9 post-treatment, significant differences were found between treated and non-treated calves using various amounts of Echinacea and Pelargonium; a doses of 250 mg Echinacea and 62.5 mg Pelargonium for 5 days seems to be ideal. Echinacea purpurae and Pelargonium sidoides are able to modulate immune functions in calves.
format	article
author	Cuneyt Seckin Gamze Alpun Kalayci Nuri Turan Aysun Yilmaz Utku Y. Cizmecigil Ozge Aydin Juergen A. Richt Huseyin Yilmaz
author_facet	Cuneyt Seckin Gamze Alpun Kalayci Nuri Turan Aysun Yilmaz Utku Y. Cizmecigil Ozge Aydin Juergen A. Richt Huseyin Yilmaz
author_sort	Cuneyt Seckin
title	Immunomodulatory effects of Echinacea and Pelargonium on the innate and adoptive immunity in calves
title_short	Immunomodulatory effects of Echinacea and Pelargonium on the innate and adoptive immunity in calves
title_full	Immunomodulatory effects of Echinacea and Pelargonium on the innate and adoptive immunity in calves
title_fullStr	Immunomodulatory effects of Echinacea and Pelargonium on the innate and adoptive immunity in calves
title_full_unstemmed	Immunomodulatory effects of Echinacea and Pelargonium on the innate and adoptive immunity in calves
title_sort	immunomodulatory effects of echinacea and pelargonium on the innate and adoptive immunity in calves
publisher	Taylor & Francis Group
publishDate	2018
url	https://doaj.org/article/742e2f9364424447883c16f6e7a09011
work_keys_str_mv	AT cuneytseckin immunomodulatoryeffectsofechinaceaandpelargoniumontheinnateandadoptiveimmunityincalves AT gamzealpunkalayci immunomodulatoryeffectsofechinaceaandpelargoniumontheinnateandadoptiveimmunityincalves AT nurituran immunomodulatoryeffectsofechinaceaandpelargoniumontheinnateandadoptiveimmunityincalves AT aysunyilmaz immunomodulatoryeffectsofechinaceaandpelargoniumontheinnateandadoptiveimmunityincalves AT utkuycizmecigil immunomodulatoryeffectsofechinaceaandpelargoniumontheinnateandadoptiveimmunityincalves AT ozgeaydin immunomodulatoryeffectsofechinaceaandpelargoniumontheinnateandadoptiveimmunityincalves AT juergenaricht immunomodulatoryeffectsofechinaceaandpelargoniumontheinnateandadoptiveimmunityincalves AT huseyinyilmaz immunomodulatoryeffectsofechinaceaandpelargoniumontheinnateandadoptiveimmunityincalves
_version_	1718409541070094336

Immunomodulatory effects of Echinacea and Pelargonium on the innate and adoptive immunity in calves

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