Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan

Mohamad I Jarrah,1 Nasr Alrabadi,2 Karem H Alzoubi3 1Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Pharmacology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan; 3Department of Clinical...

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Autores principales:	Jarrah MI, Alrabadi N, Alzoubi KH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Coronary Stent System DESyne stent Ischemic Heart Disease (IHD). Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/7431a71d1afa44f3bb483b024e37a846
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spelling	oai:doaj.org-article:7431a71d1afa44f3bb483b024e37a8462021-12-02T06:24:38ZApplying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan1179-1470https://doaj.org/article/7431a71d1afa44f3bb483b024e37a8462018-11-01T00:00:00Zhttps://www.dovepress.com/applying-desyne-coronary-stent-system-in-patients-with-ischemic-heart--peer-reviewed-article-MDERhttps://doaj.org/toc/1179-1470Mohamad I Jarrah,1 Nasr Alrabadi,2 Karem H Alzoubi3 1Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Pharmacology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan; 3Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan Background: The safety and efficacy of drug-eluting coronary stenting have been established for various degrees of severity of coronary artery disease. The DESyne is a contemporary cobalt–chromium thin-strut stent which has been studied in low-risk patients so far. Aim: The aim of this study was to evaluate the safety, efficacy and performance of the DESyne stent in patients with an indication for coronary stent implantation at the King Abdullah University Hospital (KAUH), Jordan. Patients and methods: Hospital records for all patients implanted with DESyne stent were retrospectively reviewed. Specific clinical events were recorded for all cases, and their incidence rates were estimated by the Kaplan–Meier method. A total of 715 patients (79.3% males and 58.3% with diabetes) with a mean age of 57.8±10.3 years were enrolled in this study. An acute coronary syndrome was the most frequent indication for stenting in 86.3% of the patients (unstable angina 72.0%, myocardial infarction [MI] 14.3%). A total of 849 lesions (1.2 lesions/patient) were treated with the DESyne stent. Results: After 1 year of follow-up, the death rates from cardiac or noncardiac causes were 0.6% and 1.1%, respectively. MI was observed in 0.9% of the cases, and an ischemia-driven revascularization was performed in 0.8% of them. The definite/probable stent thrombosis rate was 1.1%. Conclusion: Favorable clinical event rates including cardiac death, MI and stent thrombosis were observed for the DESyne stent in ischemic heart patients especially those with high prevalence of diabetes mellitus and acute coronary syndrome. Keywords: coronary stent system, DESyne stent, ischemic heart diseaseJarrah MIAlrabadi NAlzoubi KHDove Medical PressarticleCoronary Stent SystemDESyne stentIschemic Heart Disease (IHD).Medical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol Volume 11, Pp 405-412 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Coronary Stent System DESyne stent Ischemic Heart Disease (IHD). Medical technology R855-855.5
spellingShingle	Coronary Stent System DESyne stent Ischemic Heart Disease (IHD). Medical technology R855-855.5 Jarrah MI Alrabadi N Alzoubi KH Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan
description	Mohamad I Jarrah,1 Nasr Alrabadi,2 Karem H Alzoubi3 1Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Pharmacology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan; 3Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan Background: The safety and efficacy of drug-eluting coronary stenting have been established for various degrees of severity of coronary artery disease. The DESyne is a contemporary cobalt–chromium thin-strut stent which has been studied in low-risk patients so far. Aim: The aim of this study was to evaluate the safety, efficacy and performance of the DESyne stent in patients with an indication for coronary stent implantation at the King Abdullah University Hospital (KAUH), Jordan. Patients and methods: Hospital records for all patients implanted with DESyne stent were retrospectively reviewed. Specific clinical events were recorded for all cases, and their incidence rates were estimated by the Kaplan–Meier method. A total of 715 patients (79.3% males and 58.3% with diabetes) with a mean age of 57.8±10.3 years were enrolled in this study. An acute coronary syndrome was the most frequent indication for stenting in 86.3% of the patients (unstable angina 72.0%, myocardial infarction [MI] 14.3%). A total of 849 lesions (1.2 lesions/patient) were treated with the DESyne stent. Results: After 1 year of follow-up, the death rates from cardiac or noncardiac causes were 0.6% and 1.1%, respectively. MI was observed in 0.9% of the cases, and an ischemia-driven revascularization was performed in 0.8% of them. The definite/probable stent thrombosis rate was 1.1%. Conclusion: Favorable clinical event rates including cardiac death, MI and stent thrombosis were observed for the DESyne stent in ischemic heart patients especially those with high prevalence of diabetes mellitus and acute coronary syndrome. Keywords: coronary stent system, DESyne stent, ischemic heart disease
format	article
author	Jarrah MI Alrabadi N Alzoubi KH
author_facet	Jarrah MI Alrabadi N Alzoubi KH
author_sort	Jarrah MI
title	Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan
title_short	Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan
title_full	Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan
title_fullStr	Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan
title_full_unstemmed	Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan
title_sort	applying desyne coronary stent system in patients with ischemic heart disease: experience from jordan
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/7431a71d1afa44f3bb483b024e37a846
work_keys_str_mv	AT jarrahmi applyingdesynecoronarystentsysteminpatientswithischemicheartdiseaseexperiencefromjordan AT alrabadin applyingdesynecoronarystentsysteminpatientswithischemicheartdiseaseexperiencefromjordan AT alzoubikh applyingdesynecoronarystentsysteminpatientswithischemicheartdiseaseexperiencefromjordan
_version_	1718399940858740736

Applying DESyne coronary stent system in patients with ischemic heart disease: experience from Jordan

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