Genome-wide chromatin accessibility is restricted by ANP32E

Chromatin state underlies cellular function, and transcription factor binding patterns along with epigenetic marks define chromatin state. Here the authors show that the histone chaperone ANP32E functions through regulation of H2A.Z to restrict genome-wide chromatin accessibility and to inhibit gene...

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Bibliographic Details
Main Authors: Kristin E. Murphy, Fanju W. Meng, Claire E. Makowski, Patrick J. Murphy
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/743c4f320d424be182bff020e0814e30
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