Effect of MHC Linked 7-Gene Signature on Delayed Hepatocellular Carcinoma Recurrence

Effect of MHC Linked 7-Gene Signature on Delayed Hepatocellular Carcinoma Recurrence

Dysregulated immune response significantly affects hepatocellular carcinoma’s (HCC) prognosis. Human Leukocyte Antigens are key in devising immune responses against HCC. Here, we investigated how HLAs modulate HCC development at the transcriptomic level. RNA-seq data of 576 patients from two indepen...

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Autores principales: Fomaz Tariq, Walizeb Khan, Washaakh Ahmad, Syeda Kiran Riaz, Mahvish Khan, Subuhi Sherwani, Shafiul Haque, Muhammad Faraz Arshad Malik, Muhammad Jahangir Iftikhar, Saif Khan, Farhan Haq
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
MHC
HCC
gene signature
HLAs
immune-modulators
Medicine
R
Acceso en línea:https://doaj.org/article/743d35859f7e4355b9636a3e4b6881a8
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