Under-dominance constrains the evolution of negative autoregulation in diploids.

Regulatory networks have evolved to allow gene expression to rapidly track changes in the environment as well as to buffer perturbations and maintain cellular homeostasis in the absence of change. Theoretical work and empirical investigation in Escherichia coli have shown that negative autoregulatio...

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Bibliographic Details
Main Authors: Alexander J Stewart, Robert M Seymour, Andrew Pomiankowski, Max Reuter
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Online Access:https://doaj.org/article/743f062e6c674f6187f9401a65a88c92
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