Both strands of siRNA have potential to guide posttranscriptional gene silencing in mammalian cells.

Both strands of siRNA have potential to guide posttranscriptional gene silencing in mammalian cells.

Despite the widespread application of RNA interference (RNAi) as a research tool for diverse purposes, the key step of strand selection of siRNAs during the formation of RNA-induced silencing complex (RISC) remains poorly understood. Here, using siRNAs targeted to the complementary region of Survivi...

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Autores principales: Jun-Xia Wei, Jie Yang, Ji-Feng Sun, Lin-Tao Jia, Yong Zhang, Hui-Zhong Zhang, Xia Li, Yan-Ling Meng, Li-Bo Yao, An-Gang Yang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/743f2bfdc23241a79646ee06eda58d82
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