The relationship between Graves’ ophthalmopathy and dry eye syndrome
Jessica H Selter,1 Anisa I Gire,2 Shameema Sikder2 1Johns Hopkins School of Medicine, 2Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA Background: A complex relationship between Graves’ ophthalmopathy (GO) and dry eye syndrome exists. N...
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Dove Medical Press
2014
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oai:doaj.org-article:7440abacf2d5498fa1fd2d2f97d9d07e2021-12-02T01:26:05ZThe relationship between Graves’ ophthalmopathy and dry eye syndrome1177-5483https://doaj.org/article/7440abacf2d5498fa1fd2d2f97d9d07e2014-12-01T00:00:00Zhttp://www.dovepress.com/the-relationship-between-gravesrsquo-ophthalmopathy-and-dry-eye-syndro-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483 Jessica H Selter,1 Anisa I Gire,2 Shameema Sikder2 1Johns Hopkins School of Medicine, 2Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA Background: A complex relationship between Graves’ ophthalmopathy (GO) and dry eye syndrome exists. New research brings more insight into the association between these two diseases.Methods: A review of the literature was conducted using the query terms “Graves’ Ophthalmopathy”, “Thyroid Eye Disease”, and “Dry Eye” in MedLine (PubMed) and Scopus. A total of 55 papers were reviewed. Case reports were excluded.Conclusion: This review paper shows the close relationship between dry eye syndrome and GO. The underlying mechanisms behind their association suggest mechanical impairment of orbital muscles and immune-mediated lacrimal gland dysfunction as the causes of dry eye in GO patients. However, there are a variety of treatment options available for patients with GO with signs of dry eye, which help combat this issue. Keywords: Graves’ ophthalmopathy, dry eye, thyroid eye disease, ocular inflammationSelter JHGire AISikder SDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 57-62 (2014) |
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DOAJ |
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DOAJ |
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EN |
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Ophthalmology RE1-994 |
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Ophthalmology RE1-994 Selter JH Gire AI Sikder S The relationship between Graves’ ophthalmopathy and dry eye syndrome |
| description |
Jessica H Selter,1 Anisa I Gire,2 Shameema Sikder2 1Johns Hopkins School of Medicine, 2Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA Background: A complex relationship between Graves’ ophthalmopathy (GO) and dry eye syndrome exists. New research brings more insight into the association between these two diseases.Methods: A review of the literature was conducted using the query terms “Graves’ Ophthalmopathy”, “Thyroid Eye Disease”, and “Dry Eye” in MedLine (PubMed) and Scopus. A total of 55 papers were reviewed. Case reports were excluded.Conclusion: This review paper shows the close relationship between dry eye syndrome and GO. The underlying mechanisms behind their association suggest mechanical impairment of orbital muscles and immune-mediated lacrimal gland dysfunction as the causes of dry eye in GO patients. However, there are a variety of treatment options available for patients with GO with signs of dry eye, which help combat this issue. Keywords: Graves’ ophthalmopathy, dry eye, thyroid eye disease, ocular inflammation |
| format |
article |
| author |
Selter JH Gire AI Sikder S |
| author_facet |
Selter JH Gire AI Sikder S |
| author_sort |
Selter JH |
| title |
The relationship between Graves’ ophthalmopathy and dry eye syndrome |
| title_short |
The relationship between Graves’ ophthalmopathy and dry eye syndrome |
| title_full |
The relationship between Graves’ ophthalmopathy and dry eye syndrome |
| title_fullStr |
The relationship between Graves’ ophthalmopathy and dry eye syndrome |
| title_full_unstemmed |
The relationship between Graves’ ophthalmopathy and dry eye syndrome |
| title_sort |
relationship between graves’ ophthalmopathy and dry eye syndrome |
| publisher |
Dove Medical Press |
| publishDate |
2014 |
| url |
https://doaj.org/article/7440abacf2d5498fa1fd2d2f97d9d07e |
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