Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction

Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction

Aging induces cardiovascular disease, but which RNA molecules control cardiac aging is poorly understood. Here the authors identified the aging-regulated non-coding RNA Sarrah, which controls cardiomyocyte survival and cardiac function by inducing cardioprotective genes.

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Autores principales: D. Julia Trembinski, Diewertje I. Bink, Kosta Theodorou, Janina Sommer, Ariane Fischer, Anke van Bergen, Chao-Chung Kuo, Ivan G. Costa, Christoph Schürmann, Matthias S. Leisegang, Ralf P. Brandes, Tijna Alekseeva, Boris Brill, Astrid Wietelmann, Christopher N. Johnson, Alexander Spring-Connell, Manuel Kaulich, Stanislas Werfel, Stefan Engelhardt, Marc N. Hirt, Kaja Yorgan, Thomas Eschenhagen, Luisa Kirchhof, Patrick Hofmann, Nicolas Jaé, Ilka Wittig, Nazha Hamdani, Corinne Bischof, Jaya Krishnan, Riekelt H. Houtkooper, Stefanie Dimmeler, Reinier A. Boon
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/7441973a82494a94a2d3de6efa08b38c
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spelling oai:doaj.org-article:7441973a82494a94a2d3de6efa08b38c2021-12-02T17:32:42ZAging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction10.1038/s41467-020-15995-22041-1723https://doaj.org/article/7441973a82494a94a2d3de6efa08b38c2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15995-2https://doaj.org/toc/2041-1723Aging induces cardiovascular disease, but which RNA molecules control cardiac aging is poorly understood. Here the authors identified the aging-regulated non-coding RNA Sarrah, which controls cardiomyocyte survival and cardiac function by inducing cardioprotective genes.D. Julia TrembinskiDiewertje I. BinkKosta TheodorouJanina SommerAriane FischerAnke van BergenChao-Chung KuoIvan G. CostaChristoph SchürmannMatthias S. LeisegangRalf P. BrandesTijna AlekseevaBoris BrillAstrid WietelmannChristopher N. JohnsonAlexander Spring-ConnellManuel KaulichStanislas WerfelStefan EngelhardtMarc N. HirtKaja YorganThomas EschenhagenLuisa KirchhofPatrick HofmannNicolas JaéIlka WittigNazha HamdaniCorinne BischofJaya KrishnanRiekelt H. HoutkooperStefanie DimmelerReinier A. BoonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
D. Julia Trembinski
Diewertje I. Bink
Kosta Theodorou
Janina Sommer
Ariane Fischer
Anke van Bergen
Chao-Chung Kuo
Ivan G. Costa
Christoph Schürmann
Matthias S. Leisegang
Ralf P. Brandes
Tijna Alekseeva
Boris Brill
Astrid Wietelmann
Christopher N. Johnson
Alexander Spring-Connell
Manuel Kaulich
Stanislas Werfel
Stefan Engelhardt
Marc N. Hirt
Kaja Yorgan
Thomas Eschenhagen
Luisa Kirchhof
Patrick Hofmann
Nicolas Jaé
Ilka Wittig
Nazha Hamdani
Corinne Bischof
Jaya Krishnan
Riekelt H. Houtkooper
Stefanie Dimmeler
Reinier A. Boon
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction
description Aging induces cardiovascular disease, but which RNA molecules control cardiac aging is poorly understood. Here the authors identified the aging-regulated non-coding RNA Sarrah, which controls cardiomyocyte survival and cardiac function by inducing cardioprotective genes.
format article
author D. Julia Trembinski
Diewertje I. Bink
Kosta Theodorou
Janina Sommer
Ariane Fischer
Anke van Bergen
Chao-Chung Kuo
Ivan G. Costa
Christoph Schürmann
Matthias S. Leisegang
Ralf P. Brandes
Tijna Alekseeva
Boris Brill
Astrid Wietelmann
Christopher N. Johnson
Alexander Spring-Connell
Manuel Kaulich
Stanislas Werfel
Stefan Engelhardt
Marc N. Hirt
Kaja Yorgan
Thomas Eschenhagen
Luisa Kirchhof
Patrick Hofmann
Nicolas Jaé
Ilka Wittig
Nazha Hamdani
Corinne Bischof
Jaya Krishnan
Riekelt H. Houtkooper
Stefanie Dimmeler
Reinier A. Boon
author_facet D. Julia Trembinski
Diewertje I. Bink
Kosta Theodorou
Janina Sommer
Ariane Fischer
Anke van Bergen
Chao-Chung Kuo
Ivan G. Costa
Christoph Schürmann
Matthias S. Leisegang
Ralf P. Brandes
Tijna Alekseeva
Boris Brill
Astrid Wietelmann
Christopher N. Johnson
Alexander Spring-Connell
Manuel Kaulich
Stanislas Werfel
Stefan Engelhardt
Marc N. Hirt
Kaja Yorgan
Thomas Eschenhagen
Luisa Kirchhof
Patrick Hofmann
Nicolas Jaé
Ilka Wittig
Nazha Hamdani
Corinne Bischof
Jaya Krishnan
Riekelt H. Houtkooper
Stefanie Dimmeler
Reinier A. Boon
author_sort D. Julia Trembinski
title Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction
title_short Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction
title_full Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction
title_fullStr Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction
title_full_unstemmed Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction
title_sort aging-regulated anti-apoptotic long non-coding rna sarrah augments recovery from acute myocardial infarction
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/7441973a82494a94a2d3de6efa08b38c
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