A genetic variant in SLC30A2 causes breast dysfunction during lactation by inducing ER stress, oxidative stress and epithelial barrier defects
Abstract SLC30A2 encodes a zinc (Zn) transporter (ZnT2) that imports Zn into vesicles in highly-specialized secretory cells. Numerous mutations and non-synonymous variants in ZnT2 have been reported in humans and in breastfeeding women; ZnT2 variants are associated with abnormally low milk Zn levels...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
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Nature Portfolio
2018
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/7442bfde707e4e3ebdaa7b0c56fea71b |
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