Mycobacteria bypass mucosal NF-kB signalling to induce an epithelial anti-inflammatory IL-22 and IL-10 response.

The mechanisms by which mycobacteria subvert the inflammatory defence to establish chronic infection remain an unresolved question in the pathogenesis of tuberculosis. Using primary epithelial cells, we have analysed mycobacteria induced epithelial signalling pathways from activation of TLRs to cyto...

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Autores principales: Nataliya Lutay, Gisela Håkansson, Nader Alaridah, Oskar Hallgren, Gunilla Westergren-Thorsson, Gabriela Godaly
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/744f80ce2ac64784af9e92be1f480153
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