INDICES OF IMMUNE RESPONSE IN PATIENTS OF FALCIPARUM MALARIA IN REPUBLIC OF GUINEA

Malaria in the Republic of Guinea is the main cause of morbidity and lethality. It takes the first place in number of all visits in medical service (30–40%) and is the main cause of hospital death. One records annually more than 8 millions malaria cases, and about 60 000 children deaths. Results of...

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Autores principales:	M. Y. Boiro, S. Boumbali, O. K. Konstantinov, S. Kalivogui, M. Koulibali, A. S. Bah
Formato:	article
Lenguaje:	RU
Publicado:	Sankt-Peterburg : NIIÈM imeni Pastera 2016
Materias:	falciparum malaria antibodies immunoglobulins republic of guinea Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/745ce38f335f4b0da444432fc9c6c580
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spelling	oai:doaj.org-article:745ce38f335f4b0da444432fc9c6c5802021-11-22T07:09:47ZINDICES OF IMMUNE RESPONSE IN PATIENTS OF FALCIPARUM MALARIA IN REPUBLIC OF GUINEA2220-76192313-739810.15789/2220-7619-2016-2-151-156https://doaj.org/article/745ce38f335f4b0da444432fc9c6c5802016-06-01T00:00:00Zhttps://www.iimmun.ru/iimm/article/view/400https://doaj.org/toc/2220-7619https://doaj.org/toc/2313-7398Malaria in the Republic of Guinea is the main cause of morbidity and lethality. It takes the first place in number of all visits in medical service (30–40%) and is the main cause of hospital death. One records annually more than 8 millions malaria cases, and about 60 000 children deaths. Results of study of immune response changing on different disease phases in treatment of autochthon population and immune status of Europeans are presented. It was shown that immunity status (cellular and humoral) in population of Guinea (an endemic country on falciparum malaria) differs from one in Europeans living in tropics. During light forms of malaria one records an increase of T-lymphocyte and IgG number, whereas in grave cases one observed the acute decrease of these indices. The essential increase of B-lymphocyte number does not depends from gravity of disease and from malaria treatment. It was established that appearance of LSA1-41 antibodies was in a more degree in adult patients than in children. The positive correlation between IgM and IgG was established in adult patients as in children.M. Y. BoiroS. BoumbaliO. K. KonstantinovS. KalivoguiM. KoulibaliA. S. BahSankt-Peterburg : NIIÈM imeni Pasteraarticlefalciparum malariaantibodiesimmunoglobulinsrepublic of guineaInfectious and parasitic diseasesRC109-216RUInfekciâ i Immunitet, Vol 6, Iss 2, Pp 151-156 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	falciparum malaria antibodies immunoglobulins republic of guinea Infectious and parasitic diseases RC109-216
spellingShingle	falciparum malaria antibodies immunoglobulins republic of guinea Infectious and parasitic diseases RC109-216 M. Y. Boiro S. Boumbali O. K. Konstantinov S. Kalivogui M. Koulibali A. S. Bah INDICES OF IMMUNE RESPONSE IN PATIENTS OF FALCIPARUM MALARIA IN REPUBLIC OF GUINEA
description	Malaria in the Republic of Guinea is the main cause of morbidity and lethality. It takes the first place in number of all visits in medical service (30–40%) and is the main cause of hospital death. One records annually more than 8 millions malaria cases, and about 60 000 children deaths. Results of study of immune response changing on different disease phases in treatment of autochthon population and immune status of Europeans are presented. It was shown that immunity status (cellular and humoral) in population of Guinea (an endemic country on falciparum malaria) differs from one in Europeans living in tropics. During light forms of malaria one records an increase of T-lymphocyte and IgG number, whereas in grave cases one observed the acute decrease of these indices. The essential increase of B-lymphocyte number does not depends from gravity of disease and from malaria treatment. It was established that appearance of LSA1-41 antibodies was in a more degree in adult patients than in children. The positive correlation between IgM and IgG was established in adult patients as in children.
format	article
author	M. Y. Boiro S. Boumbali O. K. Konstantinov S. Kalivogui M. Koulibali A. S. Bah
author_facet	M. Y. Boiro S. Boumbali O. K. Konstantinov S. Kalivogui M. Koulibali A. S. Bah
author_sort	M. Y. Boiro
title	INDICES OF IMMUNE RESPONSE IN PATIENTS OF FALCIPARUM MALARIA IN REPUBLIC OF GUINEA
title_short	INDICES OF IMMUNE RESPONSE IN PATIENTS OF FALCIPARUM MALARIA IN REPUBLIC OF GUINEA
title_full	INDICES OF IMMUNE RESPONSE IN PATIENTS OF FALCIPARUM MALARIA IN REPUBLIC OF GUINEA
title_fullStr	INDICES OF IMMUNE RESPONSE IN PATIENTS OF FALCIPARUM MALARIA IN REPUBLIC OF GUINEA
title_full_unstemmed	INDICES OF IMMUNE RESPONSE IN PATIENTS OF FALCIPARUM MALARIA IN REPUBLIC OF GUINEA
title_sort	indices of immune response in patients of falciparum malaria in republic of guinea
publisher	Sankt-Peterburg : NIIÈM imeni Pastera
publishDate	2016
url	https://doaj.org/article/745ce38f335f4b0da444432fc9c6c580
work_keys_str_mv	AT myboiro indicesofimmuneresponseinpatientsoffalciparummalariainrepublicofguinea AT sboumbali indicesofimmuneresponseinpatientsoffalciparummalariainrepublicofguinea AT okkonstantinov indicesofimmuneresponseinpatientsoffalciparummalariainrepublicofguinea AT skalivogui indicesofimmuneresponseinpatientsoffalciparummalariainrepublicofguinea AT mkoulibali indicesofimmuneresponseinpatientsoffalciparummalariainrepublicofguinea AT asbah indicesofimmuneresponseinpatientsoffalciparummalariainrepublicofguinea
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INDICES OF IMMUNE RESPONSE IN PATIENTS OF FALCIPARUM MALARIA IN REPUBLIC OF GUINEA

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