LANA binds to multiple active viral and cellular promoters and associates with the H3K4methyltransferase hSET1 complex.

Kaposi's sarcoma-associated herpesvirus (KSHV) is a γ-herpesvirus associated with KS and two lymphoproliferative diseases. Recent studies characterized epigenetic modification of KSHV episomes during latency and determined that latency-associated genes are associated with H3K4me3 while most lyt...

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Autores principales: Jianhong Hu, Yajie Yang, Peter C Turner, Vaibhav Jain, Lauren M McIntyre, Rolf Renne
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/745d493209034533815f33e7c8622a8d
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