Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells

In secondary lymphoid organs T follicular helper (Tfh) cells help B cells to develop into memory B and plasma cells. Here, the authors show that inflamed lung becomes a reservoir of activated B cells with a germinal centre phenotype, and T cells that exhibit Tfh-like properties despite not expressin...

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Autores principales: Dana Vu Van, Katja C. Beier, Lea-Jean Pietzke, Maysun S. Al Baz, Randi K. Feist, Stephanie Gurka, Eckard Hamelmann, Richard A. Kroczek, Andreas Hutloff
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/745dc794203e438ea935aca0e77d92d9
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spelling oai:doaj.org-article:745dc794203e438ea935aca0e77d92d92021-12-02T16:58:12ZLocal T/B cooperation in inflamed tissues is supported by T follicular helper-like cells10.1038/ncomms108752041-1723https://doaj.org/article/745dc794203e438ea935aca0e77d92d92016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10875https://doaj.org/toc/2041-1723In secondary lymphoid organs T follicular helper (Tfh) cells help B cells to develop into memory B and plasma cells. Here, the authors show that inflamed lung becomes a reservoir of activated B cells with a germinal centre phenotype, and T cells that exhibit Tfh-like properties despite not expressing classical Tfh markers.Dana Vu VanKatja C. BeierLea-Jean PietzkeMaysun S. Al BazRandi K. FeistStephanie GurkaEckard HamelmannRichard A. KroczekAndreas HutloffNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dana Vu Van
Katja C. Beier
Lea-Jean Pietzke
Maysun S. Al Baz
Randi K. Feist
Stephanie Gurka
Eckard Hamelmann
Richard A. Kroczek
Andreas Hutloff
Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells
description In secondary lymphoid organs T follicular helper (Tfh) cells help B cells to develop into memory B and plasma cells. Here, the authors show that inflamed lung becomes a reservoir of activated B cells with a germinal centre phenotype, and T cells that exhibit Tfh-like properties despite not expressing classical Tfh markers.
format article
author Dana Vu Van
Katja C. Beier
Lea-Jean Pietzke
Maysun S. Al Baz
Randi K. Feist
Stephanie Gurka
Eckard Hamelmann
Richard A. Kroczek
Andreas Hutloff
author_facet Dana Vu Van
Katja C. Beier
Lea-Jean Pietzke
Maysun S. Al Baz
Randi K. Feist
Stephanie Gurka
Eckard Hamelmann
Richard A. Kroczek
Andreas Hutloff
author_sort Dana Vu Van
title Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells
title_short Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells
title_full Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells
title_fullStr Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells
title_full_unstemmed Local T/B cooperation in inflamed tissues is supported by T follicular helper-like cells
title_sort local t/b cooperation in inflamed tissues is supported by t follicular helper-like cells
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/745dc794203e438ea935aca0e77d92d9
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