Antimicrobial peptides trigger a division block in Escherichia coli through stimulation of a signalling system

The PhoQ/PhoP system regulates antimicrobial peptide defense in bacteria. Here the authors show that at sublethal concentrations of antimicrobial peptides, PhoPQ induces QueE, that then localizes to the divisome and blocks cell division independently of its function in queuosine biosynthesis.

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Autores principales:	Srujana S. Yadavalli, Jeffrey N. Carey, Rachel S. Leibman, Annie I. Chen, Andrew M. Stern, Manuela Roggiani, Andrew M. Lippa, Mark Goulian
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/745de4a346bf49efb45df9d57737e76a
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spelling	oai:doaj.org-article:745de4a346bf49efb45df9d57737e76a2021-12-02T14:39:11ZAntimicrobial peptides trigger a division block in Escherichia coli through stimulation of a signalling system10.1038/ncomms123402041-1723https://doaj.org/article/745de4a346bf49efb45df9d57737e76a2016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12340https://doaj.org/toc/2041-1723The PhoQ/PhoP system regulates antimicrobial peptide defense in bacteria. Here the authors show that at sublethal concentrations of antimicrobial peptides, PhoPQ induces QueE, that then localizes to the divisome and blocks cell division independently of its function in queuosine biosynthesis.Srujana S. YadavalliJeffrey N. CareyRachel S. LeibmanAnnie I. ChenAndrew M. SternManuela RoggianiAndrew M. LippaMark GoulianNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Srujana S. Yadavalli Jeffrey N. Carey Rachel S. Leibman Annie I. Chen Andrew M. Stern Manuela Roggiani Andrew M. Lippa Mark Goulian Antimicrobial peptides trigger a division block in Escherichia coli through stimulation of a signalling system
description	The PhoQ/PhoP system regulates antimicrobial peptide defense in bacteria. Here the authors show that at sublethal concentrations of antimicrobial peptides, PhoPQ induces QueE, that then localizes to the divisome and blocks cell division independently of its function in queuosine biosynthesis.
format	article
author	Srujana S. Yadavalli Jeffrey N. Carey Rachel S. Leibman Annie I. Chen Andrew M. Stern Manuela Roggiani Andrew M. Lippa Mark Goulian
author_facet	Srujana S. Yadavalli Jeffrey N. Carey Rachel S. Leibman Annie I. Chen Andrew M. Stern Manuela Roggiani Andrew M. Lippa Mark Goulian
author_sort	Srujana S. Yadavalli
title	Antimicrobial peptides trigger a division block in Escherichia coli through stimulation of a signalling system
title_short	Antimicrobial peptides trigger a division block in Escherichia coli through stimulation of a signalling system
title_full	Antimicrobial peptides trigger a division block in Escherichia coli through stimulation of a signalling system
title_fullStr	Antimicrobial peptides trigger a division block in Escherichia coli through stimulation of a signalling system
title_full_unstemmed	Antimicrobial peptides trigger a division block in Escherichia coli through stimulation of a signalling system
title_sort	antimicrobial peptides trigger a division block in escherichia coli through stimulation of a signalling system
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/745de4a346bf49efb45df9d57737e76a
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Antimicrobial peptides trigger a division block in Escherichia coli through stimulation of a signalling system

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