Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells

Class 1 type I CRISPR–Cas systems have not been as extensively developed for genome engineering as Class 2 systems. Here the authors modify the Type I–F CRISPR–Cas system for transcriptional activation of gene expression.

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Detalles Bibliográficos
Autores principales:	Yuxi Chen, Jiaqi Liu, Shengyao Zhi, Qi Zheng, Wenbin Ma, Junjiu Huang, Yizhi Liu, Dan Liu, Puping Liang, Zhou Songyang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/745fca160c3f4701a3aaa2ef13877121
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spelling	oai:doaj.org-article:745fca160c3f4701a3aaa2ef138771212021-12-02T17:40:27ZRepurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells10.1038/s41467-020-16880-82041-1723https://doaj.org/article/745fca160c3f4701a3aaa2ef138771212020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16880-8https://doaj.org/toc/2041-1723Class 1 type I CRISPR–Cas systems have not been as extensively developed for genome engineering as Class 2 systems. Here the authors modify the Type I–F CRISPR–Cas system for transcriptional activation of gene expression.Yuxi ChenJiaqi LiuShengyao ZhiQi ZhengWenbin MaJunjiu HuangYizhi LiuDan LiuPuping LiangZhou SongyangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuxi Chen Jiaqi Liu Shengyao Zhi Qi Zheng Wenbin Ma Junjiu Huang Yizhi Liu Dan Liu Puping Liang Zhou Songyang Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells
description	Class 1 type I CRISPR–Cas systems have not been as extensively developed for genome engineering as Class 2 systems. Here the authors modify the Type I–F CRISPR–Cas system for transcriptional activation of gene expression.
format	article
author	Yuxi Chen Jiaqi Liu Shengyao Zhi Qi Zheng Wenbin Ma Junjiu Huang Yizhi Liu Dan Liu Puping Liang Zhou Songyang
author_facet	Yuxi Chen Jiaqi Liu Shengyao Zhi Qi Zheng Wenbin Ma Junjiu Huang Yizhi Liu Dan Liu Puping Liang Zhou Songyang
author_sort	Yuxi Chen
title	Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells
title_short	Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells
title_full	Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells
title_fullStr	Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells
title_full_unstemmed	Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells
title_sort	repurposing type i–f crispr–cas system as a transcriptional activation tool in human cells
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/745fca160c3f4701a3aaa2ef13877121
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Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells

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