Live cell imaging of single RNA molecules with fluorogenic Mango II arrays

Fluorogenic RNA aptamers have been used for RNA imaging, but folding and fluorescence stability often limited their use in high resolution applications. Here the authors present an array of stably folding Mango II aptamers for imaging of coding and non-coding RNAs at single-molecule resolution, in b...

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Autores principales:	Adam D. Cawte, Peter J. Unrau, David S. Rueda
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7460f7c8bd624b6fa2e3fe48d7d0f593
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spelling	oai:doaj.org-article:7460f7c8bd624b6fa2e3fe48d7d0f5932021-12-02T14:40:40ZLive cell imaging of single RNA molecules with fluorogenic Mango II arrays10.1038/s41467-020-14932-72041-1723https://doaj.org/article/7460f7c8bd624b6fa2e3fe48d7d0f5932020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14932-7https://doaj.org/toc/2041-1723Fluorogenic RNA aptamers have been used for RNA imaging, but folding and fluorescence stability often limited their use in high resolution applications. Here the authors present an array of stably folding Mango II aptamers for imaging of coding and non-coding RNAs at single-molecule resolution, in both live and fixed cells.Adam D. CawtePeter J. UnrauDavid S. RuedaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Adam D. Cawte Peter J. Unrau David S. Rueda Live cell imaging of single RNA molecules with fluorogenic Mango II arrays
description	Fluorogenic RNA aptamers have been used for RNA imaging, but folding and fluorescence stability often limited their use in high resolution applications. Here the authors present an array of stably folding Mango II aptamers for imaging of coding and non-coding RNAs at single-molecule resolution, in both live and fixed cells.
format	article
author	Adam D. Cawte Peter J. Unrau David S. Rueda
author_facet	Adam D. Cawte Peter J. Unrau David S. Rueda
author_sort	Adam D. Cawte
title	Live cell imaging of single RNA molecules with fluorogenic Mango II arrays
title_short	Live cell imaging of single RNA molecules with fluorogenic Mango II arrays
title_full	Live cell imaging of single RNA molecules with fluorogenic Mango II arrays
title_fullStr	Live cell imaging of single RNA molecules with fluorogenic Mango II arrays
title_full_unstemmed	Live cell imaging of single RNA molecules with fluorogenic Mango II arrays
title_sort	live cell imaging of single rna molecules with fluorogenic mango ii arrays
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7460f7c8bd624b6fa2e3fe48d7d0f593
work_keys_str_mv	AT adamdcawte livecellimagingofsinglernamoleculeswithfluorogenicmangoiiarrays AT peterjunrau livecellimagingofsinglernamoleculeswithfluorogenicmangoiiarrays AT davidsrueda livecellimagingofsinglernamoleculeswithfluorogenicmangoiiarrays
_version_	1718390179790585856

Live cell imaging of single RNA molecules with fluorogenic Mango II arrays

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