Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing

Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing

Interaction between SETD2 and hnRNP L has previously been shown to be implicated in coupling gene transcription and mRNA processing. Here the authors elucidate the molecular basis of this functional interaction, showing that the RRM domain of hnRNP L possesses non-overlapping binding interfaces for...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Saikat Bhattacharya, Suman Wang, Divya Reddy, Siyuan Shen, Ying Zhang, Ning Zhang, Hua Li, Michael P. Washburn, Laurence Florens, Yunyu Shi, Jerry L. Workman, Fudong Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/746237619b684f9fad10fcff1640f5ab
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares