Global prevalence and economic and humanistic burden of astigmatism in cataract patients: a systematic literature review

David F Anderson,1 Mukesh Dhariwal,2 Christine Bouchet,3 Michael S Keith3 1University Hospital Southampton, NHS Foundation Trust, Southampton, UK; 2Novartis Ireland Ltd., Dublin, Ireland; 3Alcon Laboratories Inc., Fort Worth, TX, USA Purpose: To systematically review the published evidence on the...

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Autores principales:	Anderson DF, Dhariwal M, Bouchet C, Keith MS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Astigmatism Economic Burden Humanistic Burden Prevalence Cataract Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/7464659d2e5148c49504c22c531967ea
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spelling	oai:doaj.org-article:7464659d2e5148c49504c22c531967ea2021-12-02T01:17:57ZGlobal prevalence and economic and humanistic burden of astigmatism in cataract patients: a systematic literature review1177-5483https://doaj.org/article/7464659d2e5148c49504c22c531967ea2018-03-01T00:00:00Zhttps://www.dovepress.com/global-prevalence-and-economic-and-humanistic-burden-of-astigmatism-in-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483David F Anderson,1 Mukesh Dhariwal,2 Christine Bouchet,3 Michael S Keith3 1University Hospital Southampton, NHS Foundation Trust, Southampton, UK; 2Novartis Ireland Ltd., Dublin, Ireland; 3Alcon Laboratories Inc., Fort Worth, TX, USA Purpose: To systematically review the published evidence on the prevalence and economic and humanistic burden of astigmatism in cataract patients.Materials and methods: For this systematic literature review, the Medline, PubMed, Embase, and Cochrane databases were searched from 1996 to September 2015 for available scientific literature that met the inclusion criteria. Studies published in the English language reporting prevalence and humanistic and economic burden in patients diagnosed with cataract and astigmatism were included.Results: Of 3,649 papers reviewed, 31 studies from 32 publications met the inclusion criteria of this review. Preexisting astigmatism ≥1 D was present in up to 47% of cataract eyes. The cost burden of residual uncorrected astigmatism after cataract surgery was driven by the cost of spectacles, which was estimated to range from $2,151 to $3,440 in the US and $1,786 to $4,629 in Europe over a lifetime. In cataract patients, both preexisting and postoperative residual astigmatism were associated with poor vision-related patient satisfaction and quality of life, as well as higher spectacle burden. Astigmatism correction during cataract surgery appears to improve visual outcomes and results in overall lifetime cost savings compared to astigmatism correction with postoperative vision correction.Conclusion: There is a high prevalence of preexisting astigmatism in cataract patients. Although published data are limited, both preoperative astigmatism and postoperative residual astigmatism affect visual function and vision-related quality of life, resulting in increased humanistic burden. Suboptimal correction of astigmatism during cataract surgery drives the continuous need for vision correction with spectacles in the postoperative period. Patients must bear the out-of-pocket expenses, since payers often do not reimburse the cost of spectacles. Greater access to astigmatism correction during cataract surgery could improve visual outcomes and quality of life in patients. More research is required to gain a better understanding of the disease burden of astigmatism in cataract patients. Keywords: astigmatism, economic burden, humanistic burden, prevalence, cataractAnderson DFDhariwal MBouchet CKeith MSDove Medical PressarticleAstigmatismEconomic BurdenHumanistic BurdenPrevalenceCataractOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 439-452 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Astigmatism Economic Burden Humanistic Burden Prevalence Cataract Ophthalmology RE1-994
spellingShingle	Astigmatism Economic Burden Humanistic Burden Prevalence Cataract Ophthalmology RE1-994 Anderson DF Dhariwal M Bouchet C Keith MS Global prevalence and economic and humanistic burden of astigmatism in cataract patients: a systematic literature review
description	David F Anderson,1 Mukesh Dhariwal,2 Christine Bouchet,3 Michael S Keith3 1University Hospital Southampton, NHS Foundation Trust, Southampton, UK; 2Novartis Ireland Ltd., Dublin, Ireland; 3Alcon Laboratories Inc., Fort Worth, TX, USA Purpose: To systematically review the published evidence on the prevalence and economic and humanistic burden of astigmatism in cataract patients.Materials and methods: For this systematic literature review, the Medline, PubMed, Embase, and Cochrane databases were searched from 1996 to September 2015 for available scientific literature that met the inclusion criteria. Studies published in the English language reporting prevalence and humanistic and economic burden in patients diagnosed with cataract and astigmatism were included.Results: Of 3,649 papers reviewed, 31 studies from 32 publications met the inclusion criteria of this review. Preexisting astigmatism ≥1 D was present in up to 47% of cataract eyes. The cost burden of residual uncorrected astigmatism after cataract surgery was driven by the cost of spectacles, which was estimated to range from $2,151 to $3,440 in the US and $1,786 to $4,629 in Europe over a lifetime. In cataract patients, both preexisting and postoperative residual astigmatism were associated with poor vision-related patient satisfaction and quality of life, as well as higher spectacle burden. Astigmatism correction during cataract surgery appears to improve visual outcomes and results in overall lifetime cost savings compared to astigmatism correction with postoperative vision correction.Conclusion: There is a high prevalence of preexisting astigmatism in cataract patients. Although published data are limited, both preoperative astigmatism and postoperative residual astigmatism affect visual function and vision-related quality of life, resulting in increased humanistic burden. Suboptimal correction of astigmatism during cataract surgery drives the continuous need for vision correction with spectacles in the postoperative period. Patients must bear the out-of-pocket expenses, since payers often do not reimburse the cost of spectacles. Greater access to astigmatism correction during cataract surgery could improve visual outcomes and quality of life in patients. More research is required to gain a better understanding of the disease burden of astigmatism in cataract patients. Keywords: astigmatism, economic burden, humanistic burden, prevalence, cataract
format	article
author	Anderson DF Dhariwal M Bouchet C Keith MS
author_facet	Anderson DF Dhariwal M Bouchet C Keith MS
author_sort	Anderson DF
title	Global prevalence and economic and humanistic burden of astigmatism in cataract patients: a systematic literature review
title_short	Global prevalence and economic and humanistic burden of astigmatism in cataract patients: a systematic literature review
title_full	Global prevalence and economic and humanistic burden of astigmatism in cataract patients: a systematic literature review
title_fullStr	Global prevalence and economic and humanistic burden of astigmatism in cataract patients: a systematic literature review
title_full_unstemmed	Global prevalence and economic and humanistic burden of astigmatism in cataract patients: a systematic literature review
title_sort	global prevalence and economic and humanistic burden of astigmatism in cataract patients: a systematic literature review
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/7464659d2e5148c49504c22c531967ea
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Global prevalence and economic and humanistic burden of astigmatism in cataract patients: a systematic literature review

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