ASSOCIATION OF DIFFERENT PARAMETERS OF COMPLETE BLOOD COUNT WITH SEVERITY AND PROGNOSIS OF GUILLAIN-BARRE SYNDROME

Objective: Guillain-barré syndrome is the most common and most severe acute paralytic neuropathy. This study is also aimed at to know that if there is any association of parameters of complete blood count and whether these can be used as a prognostic marker for guillain-barré syndrome. Study Desi...

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Autores principales:	Nauman Aziz, Humera Khan, Syeda Rizwana Jafri, Fauzia Qureshi, Amna Muneeb, Ursula Akif
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	complete blood count guillain-barré syndrom severity Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/746cc392fd984af1b3d91433dd62be68
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spelling	oai:doaj.org-article:746cc392fd984af1b3d91433dd62be682021-12-02T16:27:32ZASSOCIATION OF DIFFERENT PARAMETERS OF COMPLETE BLOOD COUNT WITH SEVERITY AND PROGNOSIS OF GUILLAIN-BARRE SYNDROME0030-96482411-8842https://doaj.org/article/746cc392fd984af1b3d91433dd62be682021-06-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/6971https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: Guillain-barré syndrome is the most common and most severe acute paralytic neuropathy. This study is also aimed at to know that if there is any association of parameters of complete blood count and whether these can be used as a prognostic marker for guillain-barré syndrome. Study Design: Retrospective cross-sectional. Place and Duration of Study: Sahiwal Medical College Sahiwal, from Oct 2019 to Aug 2020. Methodology: This retrospective cross-sectional study was conducted at Sahiwal Medical College Sahiwal, from Oct 2019 to Aug 2020 after approval from Institutional Review Board. The data was assessed by SPSS-26. Frequency distributions of study participants were calculated. Significance of the associations was assessed by Kruskal-Wallis test and one way ANOVA test. A p-value <0.05 was taken as statistically significant. Results: Male were predominant among guillain-barré syndrome patients presenting at DHQ Hospital, Govt. Haji Abdul Qayyum Hospital Sahiwal and Surayya Azeem Teaching Hospital Lahore (65.2%). Most of the patients were in the mild category of guillain-barré syndrome (60.8%), 26% in moderate and 14.2% in severe category. We also calculated complete blood count of all study participants and calculated normality of data. We made two tables depending upon the normality of the data and cross tabulated them with severity of guillain-barré syndrome. The parameters with skewed distribution cross tabulated with severity of guillain-barré syndrome. Platelets counts showed highly significant results (p=0.04). Among the variables which were normally distributed, red blood cell count showed highly significant results when compared with severity of guillain-barré syndrome (p=0.02). Conclusion: There is strong association of some parameters of complete blood count and these can also be used as prognostic markers in severity of guillain-barré syndrome though a more detailed study with larger sample size is needed.Nauman AzizHumera KhanSyeda Rizwana JafriFauzia QureshiAmna MuneebUrsula AkifArmy Medical College Rawalpindiarticlecomplete blood countguillain-barré syndromseverityMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss 3, Pp 814-817 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	complete blood count guillain-barré syndrom severity Medicine R Medicine (General) R5-920
spellingShingle	complete blood count guillain-barré syndrom severity Medicine R Medicine (General) R5-920 Nauman Aziz Humera Khan Syeda Rizwana Jafri Fauzia Qureshi Amna Muneeb Ursula Akif ASSOCIATION OF DIFFERENT PARAMETERS OF COMPLETE BLOOD COUNT WITH SEVERITY AND PROGNOSIS OF GUILLAIN-BARRE SYNDROME
description	Objective: Guillain-barré syndrome is the most common and most severe acute paralytic neuropathy. This study is also aimed at to know that if there is any association of parameters of complete blood count and whether these can be used as a prognostic marker for guillain-barré syndrome. Study Design: Retrospective cross-sectional. Place and Duration of Study: Sahiwal Medical College Sahiwal, from Oct 2019 to Aug 2020. Methodology: This retrospective cross-sectional study was conducted at Sahiwal Medical College Sahiwal, from Oct 2019 to Aug 2020 after approval from Institutional Review Board. The data was assessed by SPSS-26. Frequency distributions of study participants were calculated. Significance of the associations was assessed by Kruskal-Wallis test and one way ANOVA test. A p-value <0.05 was taken as statistically significant. Results: Male were predominant among guillain-barré syndrome patients presenting at DHQ Hospital, Govt. Haji Abdul Qayyum Hospital Sahiwal and Surayya Azeem Teaching Hospital Lahore (65.2%). Most of the patients were in the mild category of guillain-barré syndrome (60.8%), 26% in moderate and 14.2% in severe category. We also calculated complete blood count of all study participants and calculated normality of data. We made two tables depending upon the normality of the data and cross tabulated them with severity of guillain-barré syndrome. The parameters with skewed distribution cross tabulated with severity of guillain-barré syndrome. Platelets counts showed highly significant results (p=0.04). Among the variables which were normally distributed, red blood cell count showed highly significant results when compared with severity of guillain-barré syndrome (p=0.02). Conclusion: There is strong association of some parameters of complete blood count and these can also be used as prognostic markers in severity of guillain-barré syndrome though a more detailed study with larger sample size is needed.
format	article
author	Nauman Aziz Humera Khan Syeda Rizwana Jafri Fauzia Qureshi Amna Muneeb Ursula Akif
author_facet	Nauman Aziz Humera Khan Syeda Rizwana Jafri Fauzia Qureshi Amna Muneeb Ursula Akif
author_sort	Nauman Aziz
title	ASSOCIATION OF DIFFERENT PARAMETERS OF COMPLETE BLOOD COUNT WITH SEVERITY AND PROGNOSIS OF GUILLAIN-BARRE SYNDROME
title_short	ASSOCIATION OF DIFFERENT PARAMETERS OF COMPLETE BLOOD COUNT WITH SEVERITY AND PROGNOSIS OF GUILLAIN-BARRE SYNDROME
title_full	ASSOCIATION OF DIFFERENT PARAMETERS OF COMPLETE BLOOD COUNT WITH SEVERITY AND PROGNOSIS OF GUILLAIN-BARRE SYNDROME
title_fullStr	ASSOCIATION OF DIFFERENT PARAMETERS OF COMPLETE BLOOD COUNT WITH SEVERITY AND PROGNOSIS OF GUILLAIN-BARRE SYNDROME
title_full_unstemmed	ASSOCIATION OF DIFFERENT PARAMETERS OF COMPLETE BLOOD COUNT WITH SEVERITY AND PROGNOSIS OF GUILLAIN-BARRE SYNDROME
title_sort	association of different parameters of complete blood count with severity and prognosis of guillain-barre syndrome
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doaj.org/article/746cc392fd984af1b3d91433dd62be68
work_keys_str_mv	AT naumanaziz associationofdifferentparametersofcompletebloodcountwithseverityandprognosisofguillainbarresyndrome AT humerakhan associationofdifferentparametersofcompletebloodcountwithseverityandprognosisofguillainbarresyndrome AT syedarizwanajafri associationofdifferentparametersofcompletebloodcountwithseverityandprognosisofguillainbarresyndrome AT fauziaqureshi associationofdifferentparametersofcompletebloodcountwithseverityandprognosisofguillainbarresyndrome AT amnamuneeb associationofdifferentparametersofcompletebloodcountwithseverityandprognosisofguillainbarresyndrome AT ursulaakif associationofdifferentparametersofcompletebloodcountwithseverityandprognosisofguillainbarresyndrome
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ASSOCIATION OF DIFFERENT PARAMETERS OF COMPLETE BLOOD COUNT WITH SEVERITY AND PROGNOSIS OF GUILLAIN-BARRE SYNDROME

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