Myocardial Recovery and the Failing Heart: Medical, Device and Mechanical Methods

Background: Cardiac remodeling describes the molecular, cellular, and interstitial changes that cause the ventricle to develop pathologic geometry as heart failure progresses. Reverse remodeling, or the healing of a failing heart, leads to improved mortality and quality of life. Findings: Therapies...

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Autores principales:	Judith Z. Goldfinger, Ajith P. Nair
Formato:	article
Lenguaje:	EN
Publicado:	Ubiquity Press 2014
Materias:	cardiac remodeling congestive heart failure left ventricular dysfunction myocardial recovery reverse remodeling ventricular assist devices Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/746ea9985a414359a30e50d5c6d8dbce
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spelling	oai:doaj.org-article:746ea9985a414359a30e50d5c6d8dbce2021-12-02T01:27:06ZMyocardial Recovery and the Failing Heart: Medical, Device and Mechanical Methods2214-999610.1016/j.aogh.2013.12.006https://doaj.org/article/746ea9985a414359a30e50d5c6d8dbce2014-04-01T00:00:00Zhttps://annalsofglobalhealth.org/articles/75https://doaj.org/toc/2214-9996Background: Cardiac remodeling describes the molecular, cellular, and interstitial changes that cause the ventricle to develop pathologic geometry as heart failure progresses. Reverse remodeling, or the healing of a failing heart, leads to improved mortality and quality of life. Findings: Therapies that lead to reverse remodeling include medications such as β-blockers and angiotensin-converting enzyme inhibitors; cardiac resynchronization therapy with biventricular pacing; and mechanical support with left ventricular assist devices. Conclusions: Further study is needed to better predict which patients will benefit most from these therapies and will then go on to experience reverse remodeling and myocardial recovery.Judith Z. GoldfingerAjith P. NairUbiquity Pressarticlecardiac remodelingcongestive heart failureleft ventricular dysfunctionmyocardial recoveryreverse remodelingventricular assist devicesInfectious and parasitic diseasesRC109-216Public aspects of medicineRA1-1270ENAnnals of Global Health, Vol 80, Iss 1, Pp 55-60 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiac remodeling congestive heart failure left ventricular dysfunction myocardial recovery reverse remodeling ventricular assist devices Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
spellingShingle	cardiac remodeling congestive heart failure left ventricular dysfunction myocardial recovery reverse remodeling ventricular assist devices Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270 Judith Z. Goldfinger Ajith P. Nair Myocardial Recovery and the Failing Heart: Medical, Device and Mechanical Methods
description	Background: Cardiac remodeling describes the molecular, cellular, and interstitial changes that cause the ventricle to develop pathologic geometry as heart failure progresses. Reverse remodeling, or the healing of a failing heart, leads to improved mortality and quality of life. Findings: Therapies that lead to reverse remodeling include medications such as β-blockers and angiotensin-converting enzyme inhibitors; cardiac resynchronization therapy with biventricular pacing; and mechanical support with left ventricular assist devices. Conclusions: Further study is needed to better predict which patients will benefit most from these therapies and will then go on to experience reverse remodeling and myocardial recovery.
format	article
author	Judith Z. Goldfinger Ajith P. Nair
author_facet	Judith Z. Goldfinger Ajith P. Nair
author_sort	Judith Z. Goldfinger
title	Myocardial Recovery and the Failing Heart: Medical, Device and Mechanical Methods
title_short	Myocardial Recovery and the Failing Heart: Medical, Device and Mechanical Methods
title_full	Myocardial Recovery and the Failing Heart: Medical, Device and Mechanical Methods
title_fullStr	Myocardial Recovery and the Failing Heart: Medical, Device and Mechanical Methods
title_full_unstemmed	Myocardial Recovery and the Failing Heart: Medical, Device and Mechanical Methods
title_sort	myocardial recovery and the failing heart: medical, device and mechanical methods
publisher	Ubiquity Press
publishDate	2014
url	https://doaj.org/article/746ea9985a414359a30e50d5c6d8dbce
work_keys_str_mv	AT judithzgoldfinger myocardialrecoveryandthefailingheartmedicaldeviceandmechanicalmethods AT ajithpnair myocardialrecoveryandthefailingheartmedicaldeviceandmechanicalmethods
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Myocardial Recovery and the Failing Heart: Medical, Device and Mechanical Methods

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