XEN® Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma

XEN® Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma

Antonio M Fea,1 Georges M Durr,2,3 Paola Marolo,1 Lorenza Malinverni,1 Mario A Economou,4 Ike Ahmed5 1Struttura Complessa Oculistica, Città Della Salute e Della Scienza di Torino, Dipartimento di Scienze Chirurgiche - Università Degli Studi di Torino, Torino, Italy; 2Department...

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Autores principales: Fea AM, Durr GM, Marolo P, Malinverni L, Economou MA, Ahmed I
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2020
Materias:
xen gel stent
glaucoma surgery
review
efficacy
safety
needling
Ophthalmology
RE1-994
Acceso en línea:https://doaj.org/article/746fbf36252348a6a97a0c54e093f9be
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spelling oai:doaj.org-article:746fbf36252348a6a97a0c54e093f9be2021-12-02T10:21:01ZXEN® Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma1177-5483https://doaj.org/article/746fbf36252348a6a97a0c54e093f9be2020-06-01T00:00:00Zhttps://www.dovepress.com/xenreg-gel-stent-a-comprehensive-review-on-its-use-as-a-treatment-opti-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Antonio M Fea,1 Georges M Durr,2,3 Paola Marolo,1 Lorenza Malinverni,1 Mario A Economou,4 Ike Ahmed5 1Struttura Complessa Oculistica, Città Della Salute e Della Scienza di Torino, Dipartimento di Scienze Chirurgiche - Università Degli Studi di Torino, Torino, Italy; 2Department of Ophthalmology, Université de Montréal, Montréal, Québec, Canada; 3Department of Ophthalmology, Centre Hospitalier Universitaire de Montréal (CHUM), Montréal, Québec, Canada; 4Karolinska Institute, Stockholm, Sweden; 5Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, CanadaCorrespondence: Antonio M Fea Email antoniomfea@gmail.comAbstract: The XEN Gel Microstent is a subconjunctival microinvasive glaucoma surgical device developed with the aim of improving the predictability and safety profile of bleb-forming glaucoma surgical procedures. The stent is a hydrophilic tube composed of a porcine gel cross-linked with glutaraldehyde with good stability and biocompatibility with minimal tissue reaction. This device has demonstrated promising outcomes with fewer risks compared to traditional surgeries. The aim of the review is to present early studies on different designs of the XEN Gel Stent, to summarize different surgical techniques of implantation and to analyze more comprehensively the results, complications and rates of needling of the commercially available device (Xen 45). The review will address separately special cases (PXG, UVG, ICE, congenital glaucoma) and describe small series and case reports.Keywords: XEN Gel Stent, glaucoma surgery, review, efficacy, safety, needlingFea AMDurr GMMarolo PMalinverni LEconomou MAAhmed IDove Medical Pressarticlexen gel stentglaucoma surgeryreviewefficacysafetyneedlingOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 1805-1832 (2020)
institution DOAJ
collection DOAJ
language EN
topic xen gel stent
glaucoma surgery
review
efficacy
safety
needling
Ophthalmology
RE1-994
spellingShingle xen gel stent
glaucoma surgery
review
efficacy
safety
needling
Ophthalmology
RE1-994
Fea AM
Durr GM
Marolo P
Malinverni L
Economou MA
Ahmed I
XEN® Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma
description Antonio M Fea,1 Georges M Durr,2,3 Paola Marolo,1 Lorenza Malinverni,1 Mario A Economou,4 Ike Ahmed5 1Struttura Complessa Oculistica, Città Della Salute e Della Scienza di Torino, Dipartimento di Scienze Chirurgiche - Università Degli Studi di Torino, Torino, Italy; 2Department of Ophthalmology, Université de Montréal, Montréal, Québec, Canada; 3Department of Ophthalmology, Centre Hospitalier Universitaire de Montréal (CHUM), Montréal, Québec, Canada; 4Karolinska Institute, Stockholm, Sweden; 5Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, CanadaCorrespondence: Antonio M Fea Email antoniomfea@gmail.comAbstract: The XEN Gel Microstent is a subconjunctival microinvasive glaucoma surgical device developed with the aim of improving the predictability and safety profile of bleb-forming glaucoma surgical procedures. The stent is a hydrophilic tube composed of a porcine gel cross-linked with glutaraldehyde with good stability and biocompatibility with minimal tissue reaction. This device has demonstrated promising outcomes with fewer risks compared to traditional surgeries. The aim of the review is to present early studies on different designs of the XEN Gel Stent, to summarize different surgical techniques of implantation and to analyze more comprehensively the results, complications and rates of needling of the commercially available device (Xen 45). The review will address separately special cases (PXG, UVG, ICE, congenital glaucoma) and describe small series and case reports.Keywords: XEN Gel Stent, glaucoma surgery, review, efficacy, safety, needling
format article
author Fea AM
Durr GM
Marolo P
Malinverni L
Economou MA
Ahmed I
author_facet Fea AM
Durr GM
Marolo P
Malinverni L
Economou MA
Ahmed I
author_sort Fea AM
title XEN® Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma
title_short XEN® Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma
title_full XEN® Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma
title_fullStr XEN® Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma
title_full_unstemmed XEN® Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma
title_sort xen® gel stent: a comprehensive review on its use as a treatment option for refractory glaucoma
publisher Dove Medical Press
publishDate 2020
url https://doaj.org/article/746fbf36252348a6a97a0c54e093f9be
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AT malinvernil xenreggelstentacomprehensivereviewonitsuseasatreatmentoptionforrefractoryglaucoma
AT economouma xenreggelstentacomprehensivereviewonitsuseasatreatmentoptionforrefractoryglaucoma
AT ahmedi xenreggelstentacomprehensivereviewonitsuseasatreatmentoptionforrefractoryglaucoma
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